25755-73-1

Basic information

• Product Name: Benzeneethanol, b-butyl-
• CAS NO: 25755-73-1
• Molecular Formula: C12H18O
• Molecular Weight: 178.274
• Mol File: 25755-73-1.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzeneethanol, b-butyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneethanol, b-butyl-(25755-73-1)
• EPA Substance Registry System: Benzeneethanol, b-butyl-(25755-73-1)

Safety Data

• Hazardous Substances Data: 25755-73-1(Hazardous Substances Data)

Upstream product

• 88965-92-8 1-n-butyl-1-phenyl epoxide 
• 1436-34-6 1,2-Epoxyhexane 
• 108-86-1 bromobenzene 
• 2901-28-2 ethyl α-phenylhexanoate 
• 96-09-3 styrene oxide 
• 14263-32-2 lithium tetrabutylaluminate 
• 34948-25-9 n-butylcopper 
• 109-72-8 n-butyllithium 
• 693-03-8 n-butyl magnesium bromide 
• 4392-24-9 3-bromo-1-phenyl-1-propenyl bromide 

Downstream Products

• 73083-29-1 α-butylbenzeneacetaldehyde 
• 123126-66-9 (S)-2-phenylhexanol 
• 185130-36-3 Acetic acid (S)-2-phenyl-hexyl ester 
• 189816-45-3 (R)-1-acetoxy-2-phenylhexane 
• 185130-35-2 (R)-2-phenylhexan-1-ol 

Relevant articles and documents

Regiodivergent Hydroborative Ring Opening of Epoxides via Selective C-O Bond Activation

A magnesium-catalyzed regiodivergent C-O bond cleavage protocol is presented. Readily available magnesium catalysts achieve the selective hydroboration of a wide range of epoxides and oxetanes yielding secondary and tertiary alcohols in excellent yields and regioselectivities. Experimental mechanistic investigations and DFT calculations provide insight into the unexpected regiodivergence and explain the different mechanisms of the C-O bond activation and product formation.

Nickel-catalyzed regiodivergent opening of epoxides with aryl halides: Co-catalysis controls regioselectivity

Epoxides are versatile intermediates in organic synthesis, but have rarely been employed in cross-coupling reactions. We report that bipyridine-ligated nickel can mediate the addition of functionalized aryl halides, a vinyl halide, and a vinyl triflate to epoxides under reducing conditions. For terminal epoxides, the regioselectivity of the reaction depends upon the cocatalyst employed. Iodide cocatalysis results in opening at the less hindered position via an iodohydrin intermediate. Titanocene cocatalysis results in opening at the more hindered position, presumably via TiIII-mediated radical generation. 1,2-Disubstituted epoxides are opened under both conditions to form predominantly the trans product.

Gold-Catalyzed Electrophilic Addition to Arylalkynes. A Facile Method for the Regioselective Synthesis of Substituted Naphthalenes

An interesting gold-catalyzed electrophilic addition to arylalkyne to synthesize substituted naphthalenes has been presented. Different metal hexafluoroantimonates have also been found to effect the transformation. Counter anion and oxo- and alkynophilicities of catalytic gold species might play an important role in this annulation reaction.