25827-12-7Relevant articles and documents
N-alkylations of NH-sulfoximines and NH-sulfondiimines with alkyl halides mediated by potassium hydroxide in dimethyl sulfoxide
Hendriks, Christine M. M.,Bohmann, Rebekka A.,Bohlem, Marina,Bolm, Carsten
supporting information, p. 1847 - 1852 (2014/06/09)
A general method for the N-alkylation of NH-sulfoximines and NH-sulfondiimines has been developed, employing alkyl bromides with KOH in DMSO at room temperature. A variety of previously inaccessible N-alkylated sulfoximines and sulfondiimines was prepared in good to excellent yields (up to 97%). As an application, the conditions were used to access the biologically active Suloxifen.
N-dialkylaminoalkyl-S,S-diphenyl-sulfoximines, a new class of compounds with spasmolytic properties
Satzinger,Stoss
, p. 1214 - 1217 (2007/10/05)
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