258350-62-8

Basic information

• Product Name: 2-METHYL[1,2,4]TRIAZOLO[1,5-C]QUINAZOLINE-5-THIOL
• Synonyms: 2-METHYL[1,2,4]TRIAZOLO[1,5-C]QUINAZOLINE-5-THIOL
• CAS NO: 258350-62-8
• Molecular Formula: C₁₀H₈N₄S
• Molecular Weight: 216.26
• Mol File: 258350-62-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-METHYL[1,2,4]TRIAZOLO[1,5-C]QUINAZOLINE-5-THIOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL[1,2,4]TRIAZOLO[1,5-C]QUINAZOLINE-5-THIOL(258350-62-8)
• EPA Substance Registry System: 2-METHYL[1,2,4]TRIAZOLO[1,5-C]QUINAZOLINE-5-THIOL(258350-62-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 258350-62-8(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 127024-85-5 3-amino-4-imino-2-thioxo-1,2,3,4-tetrahydroquinazoline 
• 78-39-7 Triethyl orthoacetate 
• 1068-57-1 acetic acid hydrazide 
• 81431-98-3 2-cyanophenylisothiocyanate 

Relevant articles and documents

Triazoloquinazolines as a novel class of phosphodiesterase 10A (PDE10A) inhibitors

Novel triazoloquinazolines have been found as phosphodiesterase 10A (PDE10A) inhibitors. Structure-activity studies improved the initial micromolar potency which was found in the lead compound by a 100-fold identifying 5-(1H-benzoimidazol-2-ylmethylsulfan

Synthesis and reactivity of 1,2,4-triazolo[1,5-c]quinazolines

The preparation of 1,2,4-triazolo[1,5-c]quinazolines 4a-d, 5, 8a-d by cyclocondensation of 1a-c with carboxylic acids and carboxylic anhydrides, respectively, is described. By different pathways, the 5-thioxo-5,6-dihydro- 1,2,4-triazolo[1,5-c]quinazolines