25844-23-9

Basic information

• Product Name: N-phenylisobutyrimidamide
• Synonyms: N-phenylisobutyrimidamide
• CAS NO: 25844-23-9
• Molecular Weight: 162.235
• Mol File: 25844-23-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-phenylisobutyrimidamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenylisobutyrimidamide(25844-23-9)
• EPA Substance Registry System: N-phenylisobutyrimidamide(25844-23-9)

Safety Data

• Hazardous Substances Data: 25844-23-9(Hazardous Substances Data)

Upstream product

• 22007-68-7 2-methylpropanimidamide hydrochloride 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 615-42-9 1,2-Diiodobenzene 
• 57536-10-4 isobutyramidine 
• 79-30-1 isobutyryl chloride 
• 62-53-3 aniline 
• 591-50-4 iodobenzene 
• 563-83-7 ISOPROPYLAMIDE 

Downstream Products

• 50737-95-6 N-phenyl-isobutyrimidoyl chloride 
• 60986-33-6 4,5‐dimethyl‐2‐phenyl‐1H-benzoimidazole 

Relevant articles and documents

1,1-Diphosphines and divinylphosphines via base catalyzed hydrophosphination

A catalytic hydrophosphination route to 1,1-diphosphines is yet to be reported: these narrow bite angle pro-ligands have been used to great effect as ligands in homogeneous catalysis. We herein demonstrate that terminal alkynes readily undergo double hydrophosphination with HPPh2 and catalytic potassium hexamethyldisilazane (KHMDS) to generate 1,1-diphosphines. A change to H2PPh leads to the formation of P,P-divinyl phosphines.

Facile N-arylation of amidines and N,N-disubstituted amidines

A metal-free method for the N-arylation of amidines and N,N-disubstituted amidines using o-silylaryl triflate under very mild reaction conditions is developed. The reactions are compatible with a variety of functional groups. Imines can also be N-arylated by this method. Preparation of substituted phenanthridines via a Pd catalyzed intramolecular cyclization of the iodine containing N-arylation product is demonstrated.