258500-80-0Relevant articles and documents
Synthesis and biological evaluation of meperidine analogues at monoamine transporters
Lomenzo, Stacey A.,Rhoden, Jill B.,Izenwasser, Sari,Wade, Dean,Kopajtic, Theresa,Katz, Jonathan L.,Trudell, Mark L.
, p. 1336 - 1343 (2007/10/03)
A series of aryl-substituted meperidine analogues was synthesized, and the binding affinities were determined at the DAT, SERT, and NET as well as at μ-opioid receptors. Generally the analogues exhibited increased affinity for the DAT and SERT relative to