258500-81-1

Basic information

• Product Name: 4-Piperidinecarbonitrile, 4-(4-chlorophenyl)-1-methyl-
• CAS NO: 258500-81-1
• Molecular Formula: C13H15ClN2
• Molecular Weight: 234.728
• Mol File: 258500-81-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-Piperidinecarbonitrile, 4-(4-chlorophenyl)-1-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidinecarbonitrile, 4-(4-chlorophenyl)-1-methyl-(258500-81-1)
• EPA Substance Registry System: 4-Piperidinecarbonitrile, 4-(4-chlorophenyl)-1-methyl-(258500-81-1)

Safety Data

• Hazardous Substances Data: 258500-81-1(Hazardous Substances Data)

Upstream product

• 140-53-4 p-chlorobenzyl cyanide 
• 55-86-7 mechlorethamine hydrochloride 
• 593-51-1 methylamine hydrochloride 
• 74-89-5 methylamine 
• 258500-74-2 2-(4-chlorophenyl)-2-(2,2-dimethoxyethyl)-4,4-dimethoxybutyronitrile 

Downstream Products

• 906369-54-8 4-(4-chloro-phenyl)-4-cyano-piperidine-1-carboxylic acid benzyl ester 
• 906369-60-6 4-(4-chloro-phenyl)-4-(methanesulfonylamino-methyl)-piperidine-1-carboxylic acid benzyl ester 
• 258500-88-8 4-(4-chlorophenyl)-1-methylpiperidine-4-carboxylic acid ethyl ester 
• 719275-81-7 1-N-methyl-4-(4-chlorophenyl)-4-(aminomethyl)piperidine 

Relevant articles and documents

Preparation of 2,3-dihydro-1H-spiro[isoquinoline-4,4′-piperidine] via an N-sulfonyl Pictet-Spengler reaction

A high yielding synthesis of variously substituted 2,3-dihydro-1H-spiro[isoquinoline-4,4′-piperidine] is reported. N-(2-nitrophenyl)sulfonyl was successfully used as both an activating and protecting group for the key Pictet-Spengler reaction.

PIPERIDINE AMINE COMPOUNDS AND THEIR USE

Compounds having the formula[Chemical formula should be inserted here. Please see paper copy] wherein R1, R2, R3, R6, R7 and Ar are as defined in the specification, in vivo-hydrolysable precursors the