25877-35-4 Usage
Nitro-substituted benzotriazole derivative
A compound in which a nitro group (-NO2) has replaced a hydrogen atom on the benzotriazole (a 5-membered ring system with two nitrogen atoms) structure.
Corrosion inhibitor
1-Methyl-6-nitro-1H-benzotriazole is commonly used to prevent or slow down the corrosion of metals, particularly steel and aluminum.
Carboxylate-based corrosion inhibitors
The compound is particularly effective in carboxylate-based systems, which are chemical compounds containing a carboxyl group (-COOH) that can form a salt with metal ions, providing protection against corrosion.
Intermediate in synthesis
1-Methyl-6-nitro-1H-benzotriazole is used as a starting material or intermediate in the production of other chemical compounds, such as pharmaceuticals, dyes, and pigments.
Harmful if swallowed, inhaled, or in contact with skin
The compound poses a health risk if it is ingested, breathed in, or comes into contact with the skin due to its toxic nature.
Causes irritation to respiratory system and skin
Exposure to 1-Methyl-6-nitro-1H-benzotriazole may lead to inflammation and discomfort in the respiratory system and on the skin.
Handling precautions
To minimize the risks associated with 1-Methyl-6-nitro-1H-benzotriazole, it should be handled with extreme caution, following all relevant safety regulations and guidelines.
Check Digit Verification of cas no
The CAS Registry Mumber 25877-35-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,8,7 and 7 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 25877-35:
(7*2)+(6*5)+(5*8)+(4*7)+(3*7)+(2*3)+(1*5)=144
144 % 10 = 4
So 25877-35-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H6N4O2/c1-10-7-4-5(11(12)13)2-3-6(7)8-9-10/h2-4H,1H3
25877-35-4Relevant articles and documents
QUINAZOLINE COMPOUNDS USEFUL AS M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS
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Page/Page column 83, (2017/09/27)
The present invention is directed to compounds of Formula (I): (Formula (I)) and pharmaceutically acceptable salts thereof, wherein X, Y, Z, R1, R7, R8, R9, R11, n and p are defined herein. The compounds of Formula (I) are M1 receptor positive allosteric modulators that are useful in the treatment of diseases in which the M1 receptor is involved, including Alzheimer's disease, schizophrenia, pain and sleep disorders. The invention also relates to pharmaceutical compositions comprising a compound of Formula (I) and a pharmaceutically acceptable carrier, and to methods of using the compounds of Formula (I) in the treatment of diseases mediated by the M1 receptor.
8 - SUBSTITUTED 2 -AMINO - [1,2,4] TRIAZOLO [1, 5 -A] PYRAZINES AS SYK TRYROSINE KINASE INHIBITORS AND GCN2 SERIN KINASE INHIBITORS
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Page/Page column 113; 114, (2013/09/12)
Compounds of the formula I in which R1, R2 and R4 have the meanings indicated in Claim 1, are inhibitors of Syk, and can be employed, inter alia, for the treatment of cancer, rheumatoid arthritis and / or systemic lupus
Synthesis, antimicrobial data and correlation analysis in a set of 2-alkyl-5-amidobenzotriazoles
Caliendo,Novellino,Sagliocco,Santagada,Silipo,Vittoria
, p. 161 - 166 (2007/10/02)
A set of 2-alkyl-5-amidobenzotriazoles has been prepared and characterized. Shake-flask partition coefficients (log P) and capacity factors (log k') have been experimentally determined. The in vitro antimicrobial activity against Gram-positive, Gram-negat
