258870-13-2Relevant articles and documents
Use of small molecule radioligands to discover inhibitors of amyloid-beta peptide production and for diagnostic imaging
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, (2008/06/13)
This invention relates to a novel method of screening for inhibitors of beta-amyloid production, and thereby identifying such inhibitors as therapeutics for neurological and other disorders involving APP processing and beta-amyloid production. This invent
Use of small molecule radioligands to discover inhibitors of amyloid-beta peptide production and for diagnostic imaging
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, (2008/06/13)
This invention relates to a method of using radiolabelled and/or radiopharmaceutical small molecule inhibitors of beta-amyloid peptide production for the diagnosis of neurological and other disorders involving APP processing and beta-amyloid production. Furthermore, radiolabelled small molecule inhibitors identified by the methods of the present invention would be useful in the diagnosis of neurological disorders, such as Alzheimer's disease, which involve elevated levels of Aβ peptides.