259106-70-2

Basic information

• Product Name: N-tert-butyloxycarbonylphenylalanine 3,4'-O-isopropylidene-5'-pyridoxyl ester
• Synonyms: N-tert-butyloxycarbonylphenylalanine 3,4'-O-isopropylidene-5'-pyridoxyl ester
• CAS NO: 259106-70-2
• Molecular Weight: 456.539
• Mol File: 259106-70-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-tert-butyloxycarbonylphenylalanine 3,4'-O-isopropylidene-5'-pyridoxyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-tert-butyloxycarbonylphenylalanine 3,4'-O-isopropylidene-5'-pyridoxyl ester(259106-70-2)
• EPA Substance Registry System: N-tert-butyloxycarbonylphenylalanine 3,4'-O-isopropylidene-5'-pyridoxyl ester(259106-70-2)

Safety Data

• Hazardous Substances Data: 259106-70-2(Hazardous Substances Data)

Upstream product

• 58-56-0 pyridoxal hydrochloride 
• 1136-52-3 (2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 

Downstream Products

• 285131-17-1 2-[2-(2-tert-butoxycarbonylamino-4-methylsulfanyl-butyrylamino)-4-methyl-pentanoylamino]-3-phenyl-propionic acid 2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-ylmethyl ester 
• 285131-19-3 2-[2-(2-formylamino-4-methylsulfanyl-butyrylamino)-4-methyl-pentanoylamino]-3-phenyl-propionic acid 2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-ylmethyl ester 
• 285131-16-0 2-(2-tert-butoxycarbonylamino-4-methyl-pentanoylamino)-3-phenyl-propionic acid 2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-ylmethyl ester 
• 59880-97-6 formyl-methionyl-leucyl-phenylalanine 

Relevant articles and documents

The synthesis of amino acid pyridoxyl esters

A multifunctional protective group was suggested on the basis of 4,5-dihydroxymethyl-3-hydroxy-2-methylpyridine (pyridoxine). A preparative method for the synthesis of the starting compounds, pyridoxine ketals, with the use of thionyl chloride was developed, and some new amino acid derivatives, 3,4′-O-isopropylidene-5′-pyridoxyl and 3,4′-O-cyclohexylidene-5′-pyridoxyl esters, were obtained. These resist the action of trifluoroacetic, hydrochloric, hydrobromic, and hydrofluoric acids and can be cleaved by saponification, ammonolysis, hydrazinolysis, hydrogenolysis, or photolysis.