25912-37-2

Basic information

• Product Name: 3-methyl-5-nitropyrimidine-2,4(1H,3H)-dione
• CAS NO: 25912-37-2
• Molecular Formula: C₅H₅N₃O₄
• Molecular Weight: 171.1109
• Mol File: 25912-37-2.mol
• Article Data: 3

Chemical Properties

• Density: 1.59g/cm³
• Refractive Index: 1.598
• CAS DataBase Reference: 3-methyl-5-nitropyrimidine-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methyl-5-nitropyrimidine-2,4(1H,3H)-dione(25912-37-2)
• EPA Substance Registry System: 3-methyl-5-nitropyrimidine-2,4(1H,3H)-dione(25912-37-2)

Safety Data

• Hazardous Substances Data: 25912-37-2(Hazardous Substances Data)

Upstream product

• 611-08-5 5-nitrobarbituric acid 
• 74-88-4 methyl iodide 
• 608-34-4 3-methyluracil 
• 108047-30-9 3-methyl-5-nitro-1-(p-nitrophenyl)uracil 
• 6327-98-6 2-methylthio-3-methylpyrimidin-4(3H)-one 
• 37721-30-5 3-methyl-1-phenyluracil 
• 934802-64-9 3-methyl-5-nitro-1-phenyluracil 
• 128039-12-3 1-methyl-1-(3-methylamino-2-nitroacryloyl)-3-(p-nitro-phenyl)urea methylammonium salt 

Downstream Products

• 57381-15-4 3-methyl-5-amino-2,4(1H,3H)pyrimidinedione 

Relevant articles and documents

Novel Reaction of Uracil Derivatives Possessing Electron-withdrawing Groups at the 5-Position with Amines: Exchange Reaction between the N1-Portion of Uracils and Amines

The reaction of 1,3-disubstituted uracils possessing an electron-withdrawing group such as nitro, carbamoyl, and cyano at 5-position with primary amines resulted in the exchange of the N1-portion of the uracil ring with the amine moiety.The exchange reactions were influenced by the nature of substituents at the 5- and N1-position.The reaction sequence is explained in terms of addition, ring-opening, and ring-closure.

NOVEL REACTION OF 5-NITRO(OR CARBAMOYL)URACIL DERIVATIVES WITH AMINES. THERMAL EXCHANGE REACTION OF N1-PORTION OF THE URACILS FOR AMINES VIA RING-OPENING AND RING-CLOSURE PROCESSES

The reaction of 1,3-disubstituted uracils possessing an electron withdrawing group at the 5-position with amines induced exchange of N1-portion of the uracil ring for amines.This reaction was accelerated by substitution of phenyl groups at the N1-position.