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259219-18-6

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259219-18-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 259219-18-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,9,2,1 and 9 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 259219-18:
(8*2)+(7*5)+(6*9)+(5*2)+(4*1)+(3*9)+(2*1)+(1*8)=156
156 % 10 = 6
So 259219-18-6 is a valid CAS Registry Number.

259219-18-6Relevant articles and documents

RXR partial agonist CBt-PMN exerts therapeutic effects on type 2 diabetes without the side effects of RXR full agonists

Kakuta, Hiroki,Yakushiji, Nobumasa,Shinozaki, Ryosuke,Ohsawa, Fuminori,Yamada, Shoya,Ohta, Yui,Kawata, Kohei,Nakayama, Mariko,Hagaya, Manabu,Fujiwara, Chisa,Makishima, Makoto,Uno, Shigeyuki,Tai, Akihiro,Maehara, Ami,Nakayama, Masaru,Oohashi, Toshitaka,Yasui, Hiroyuki,Yoshikawa, Yutaka

supporting information; experimental part, p. 427 - 432 (2012/06/30)

Treating insulin resistance and type 2 diabetes in rodents, currently known retinoid X receptor (RXR) agonists induce significant adverse effects. Here we introduce a novel RXR partial agonist CBt-PMN (11b), which shows a potent glucose-lowering effect and improvements of insulin secretion and glucose tolerance without the serious adverse effects caused by RXR full agonists. We suggest that RXR partial agonists may be a new class of antitype 2 diabetes drug candidates.

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