260050-22-4

Basic information

• Product Name: methyl 9-phenyl-2(E)-nonenoate
• Synonyms: methyl 9-phenyl-2(E)-nonenoate
• CAS NO: 260050-22-4
• Molecular Weight: 246.349
• Mol File: 260050-22-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 9-phenyl-2(E)-nonenoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 9-phenyl-2(E)-nonenoate(260050-22-4)
• EPA Substance Registry System: methyl 9-phenyl-2(E)-nonenoate(260050-22-4)

Safety Data

• Hazardous Substances Data: 260050-22-4(Hazardous Substances Data)

Upstream product

• 260050-21-3 (E)-methyl 7-phenylhept-2-enoate 
• 101689-18-3 7-phenylheptanoic acid methyl ester 
• 36884-28-3 5-phenyl-1-pentanal 
• 2270-20-4 5-Phenylpentanoic acid 
• 10521-91-2 5-phenylpentan-1-ol 
• 1067-74-9 Methyl diethylphosphonoacetate 
• 121784-15-4 7-phenylheptanal 

Downstream Products

• 260050-37-1 5-(8-phenyl-octyl)-4-tosyl-2-oxazoline 
• 221195-30-8 9-(phenyl)-nonan-1-al 
• 24197-55-5 9-phenylnonanoic acid methyl ester 

Relevant articles and documents

Synthesis and histamine H3 receptor activity of 4-(n-alkyl)-1H-imidazoles and 4-(omega-phenylalkyl)-1H-imidazoles.

The influence of lipophilic moieties attached to a 4-1H-imidazole ring on the histamine H3 receptor activity was systematically investigated. Series of 4-(n-alkyl)-1H-imidazoles and 4-(omega-phenylalkyl)-1H-imidazoles were prepared, with an alkyl chain varying from 2-9 methylene groups and from 1-9 methylene groups, respectively. The compounds were tested for their activity on the H3 receptor under in vitro conditions. For the 4-(n-alkyl)-1H-imidazoles the activity is proportional to chain length, ranging from a pA2 value of 6.3 +/- 0.2 for 4-(n-propyl)-1H-imidazole to a pA2 value of 7.2 +/- 0.1 for 4-(n-decyl)-1H-imidazole. For the series 4-(omega-phenylalkyl)-4H-imidazoles an optimum in H3 activity was found for the pentylene spacer: 4-(omega-phenylpentyl)-1H-imidazole has a pA2 value of 7.8 +/- 0.1.