26006-20-2

Basic information

• Product Name: POLY(TOLYLENE 2,4-DIISOCYANATE)
• Synonyms: POLY(TOLYLENE 2,4-DIISOCYANATE);2,4-diisocyanato-1-methyl-benzenhomopolymer;2,4-Toluenediisocyanate,homopolymer;Benzene,2,4-diisocyanato-1-methyl-,homopolymer;Poly(tolylene 2,4-diisocyanate) solution;POLY(TOLYLENE 2,4-DIISOCYANATE), 50 WT. % SOLUTION IN BUTYL ACETATE;2,4-DISOCYANATO-1-METHYLBENZENE, HOMOPLOYMER;toluene-2,4-diisocyanate homopolymer
• CAS NO: 26006-20-2
• Molecular Formula: C9H6N2O2
• Molecular Weight: 174.15614
• Product Categories: Polymers;Engineering Polymers;Polymer Science;Polyurethanes and Urethane Precursors
• Mol File: 26006-20-2.mol
• Article Data: 65

Chemical Properties

• Boiling Point: 386.8°Cat760mmHg
• Flash Point: 88 °F
• Appearance: /
• Density: 1.09 g/mL at 25 °C
• Refractive Index: n20/D 1.501
• CAS DataBase Reference: POLY(TOLYLENE 2,4-DIISOCYANATE)(CAS DataBase Reference)
• NIST Chemistry Reference: POLY(TOLYLENE 2,4-DIISOCYANATE)(26006-20-2)
• EPA Substance Registry System: POLY(TOLYLENE 2,4-DIISOCYANATE)(26006-20-2)

Safety Data

• Hazard Codes: T,Xi
• Statements: 45-10-23/24/25-42/43-67-66-41
• Safety Statements: 53-16-23-36/37/39-45-39-26
• RIDADR: UN 1866 3/PG 3
• Hazardous Substances Data: 26006-20-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H6N2O2/c1-7-2-3-8(10-5-12)4-9(7)11-6-13/h2-4H,1H3

Upstream product

• 75-44-5 phosgene 
• 95-80-7 4-methylbenzene-1,3-diamine 
• 7450-62-6 2,4-bis-(ethoxycarbonylamino)toluene 
• 201230-82-2 carbon monoxide 
• 121-14-2 2,4-dinitrotoluene 
• 6935-99-5 2,4-bis(methoxycarbonylamino)toluene 
• 60483-66-1 dipropyl (4-methyl-1,3-phenylene)dicarbamate 
• 108-71-4 3,5-diaminotoluene 
• 823-40-5 2,6-toluenediamine 
• 95-70-5 2-methyl-p-phenylenediamine 
• 102019-95-4 4-methyl-1,3-phenylenedi(carbamic acid(3-methylbutyl)ester) 
• 4223-24-9 toluene-2,4-dicarbamic acid diphenyl ester 
• 1195975-93-9 toluene-2,4-dicarbamic acid bis(2-ethylbutyl) ester 
• 7469-49-0 1-methyl-2,4-bis-(butoxycarbonylamino)-benzene 

Downstream Products

• 93427-59-9 3,3'-(4-methyl-m-phenylene)-bis-oxazolidin-2-one 
• 2131-75-1 N,N'-bis-(aziridine-1-carbonyl)-4-methyl-m-phenylenediamine 
• 102544-18-3 N,N'-(4-methyl-m-phenylene)-bis-carbamic acid bis-(2-piperidino-ethyl ester) 
• 57718-04-4 N,N'-(4-methyl-m-phenylene)-bis-carbamic acid bis-(2-morpholino-ethyl ester) 
• 7402-96-2 N,N'-bis-(2,2-dimethyl-aziridine-1-carbonyl)-4-methyl-m-phenylenediamine 
• 116598-51-7 2,4-bis-{N'-[2-(diethyl-methyl-ammonio)-ethyl]-ureido}-toluene; diiodide 
• 18751-25-2 N,N'-(4-methyl-m-phenylene)-bis-carbamic acid bis-triethylsilanyl ester 
• 124115-69-1 N,N'-(4-methyl-m-phenylene)-bis-carbamic acid bis-[3-(4-methyl-morpholinium-4-yl)-propylester]; diiodide 
• 122214-87-3 N,N'-(4-methyl-m-phenylene)-bis-carbamic acid bis-[3-(1-methyl-piperidinium-1-yl)-propylester]; diiodide 
• 10097-06-0 2,4-tolylene diurea 
• 59007-10-2 bis-(3-isocyanato-4-methyl-phenyl)-carbodiimide 
• 7450-62-6 2,4-bis-(ethoxycarbonylamino)toluene 
• 54222-26-3 2-tert-butyl-4-(3-isocyanato-4-methyl-phenyl)-3-phenyl-[1,2,4]oxadiazolidin-5-one 
• 94091-13-1 1-Cyclohexyl-3-<3-isocyanato-p-tolyl>-harnstoff 

Relevant articles and documents

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Study on the synthesis of toluene-2,4-diisocyanate via amine and carbonyl fluoride

Abstract We presented recently a synthesis of toluene-2,4-diisocyanate (TDI) as one of the nine examples to verify the feasibility of an industrial appealing two-step method for isocyanates synthesis via amines and carbonyl fluoride (COF2). Because more investigation was considered to be necessary for future industrial application, the two-step synthesis processes of TDI were studied in detail herein. The total yield of TDI increased 5.6% under the optimized experimental conditions. The influence of the excess COF2 left in the reaction system was studied carefully according to a one-pot method.

Synthesis and antitussive activity of obtucarbamate A derivatives

Obtucarbamate A was purified from Disporum cantoniense with good antitussive property. In present work, a series of obtucarbamate A derivatives were designed and synthesized from obtucarbamate A by microwave method, and their antitussive activity were evaluated. The results showed that the toluene diisocyanate was obtained with a yield of 95.1percent using a simple method, 1-methyl-2-pyrrolidinone as solvent, temperature of 190 °C, microwave irradiation at 60 W power for 30 min. All compounds have good antitussive activity, and small steric hindrance unsaturated groups of ester chains and amino groups favor activity. It is the first reported of obtucarbamate A derivatives used as antitussive, and the results provide a basis for the application of obtucarbamate derivatives as new antitussive.

ISOCYANATE PRODUCTION METHOD

An isocyanate production method according to the present invention is a method in which an isocyanate is produced by subjecting a carbamate to thermal decomposition, and includes: a step of preparing a mixture liquid containing the carbamate, an inactive solvent and a polyisocyanate compound; a step of conducting a thermal decomposition reaction of the carbamate by continuously introducing the mixture liquid into a thermal decomposition reactor; a step of collecting a low-boiling decomposition product by continuously extracting the low-boiling decomposition product in a gaseous state from the reactor, the low-boiling decomposition product having a boiling point lower than the polyisocyanate compound; and a step of collecting a high-boiling component by continuously extracting, from the reactor, a liquid phase component which is not collected in a gaseous state at the step of collecting the low-boiling decomposition product.