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260441-48-3

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260441-48-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 260441-48-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,0,4,4 and 1 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 260441-48:
(8*2)+(7*6)+(6*0)+(5*4)+(4*4)+(3*1)+(2*4)+(1*8)=113
113 % 10 = 3
So 260441-48-3 is a valid CAS Registry Number.

260441-48-3Relevant articles and documents

The discovery of CCR3/H1 dual antagonists with reduced hERG risk

Barton, Patrick,Brough, Steven,Evans, Richard,Luckhurst, Christopher A.,Mochel, Tobias,Perry, Matthew W. D.,Rigby, Aaron,Sanganee, Hitesh,Sisson, Adam,Springthorpe, Brian,Bahl, Ash,Bowers, Keith,Riley, Robert J.

, p. 6688 - 6693,6 (2012/12/12)

A series of dual CCR3/H1 antagonists based on a bispiperidine scaffold were discovered. Introduction of an acidic group overcame hERG liability. Bioavailability was optimised by modulation of physico-chemical properties and physical form to del

Chemical compounds

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, (2008/06/13)

The invention provides compounds of formula (I): as modulators of chemokine and H1 receptor activity. The compounds are especially useful in the treatment of asthma and rhinitis.

Chemical compounds

-

, (2008/06/13)

The invention concerns compounds of formula (I), and their use in therapy, particularly in the modulation of CCR3 activity.

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