26060-14-0

Basic information

• Product Name: 1-methoxy-9H-fluorene
• Synonyms: 9H-Fluorene, methoxy-
• CAS NO: 26060-14-0
• Molecular Formula: C₁₄H₁₂O
• Molecular Weight: 196.2445
• Mol File: 26060-14-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 342.9°C at 760 mmHg
• Flash Point: 136°C
• Density: 1.138g/cm³
• Vapor Pressure: 0.000145mmHg at 25°C
• Refractive Index: 1.619
• CAS DataBase Reference: 1-methoxy-9H-fluorene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methoxy-9H-fluorene(26060-14-0)
• EPA Substance Registry System: 1-methoxy-9H-fluorene(26060-14-0)

Safety Data

• Hazardous Substances Data: 26060-14-0(Hazardous Substances Data)

Usage

Derivative of fluorene

A modified version of the polycyclic aromatic hydrocarbon
1-Methoxy-9H-fluorene is derived from fluorene, which is a polycyclic aromatic hydrocarbon consisting of two benzene rings connected by a central five-membered ring.

Physical appearance

Colorless solid
This chemical compound is a colorless solid, meaning it does not have any visible color.

Solubility

Insoluble in water, soluble in organic solvents
1-Methoxy-9H-fluorene is not soluble in water but can dissolve in organic solvents such as alcohol and ether.

Uses

Organic synthesis, precursor in pharmaceutical production
It is commonly used in organic synthesis and as a precursor in the production of pharmaceuticals and other organic compounds.

Research potential

Synthesis of novel materials, study of chemical reactions
This chemical has been studied for its potential use in various applications, including as a starting material for the synthesis of novel materials and as a probe for the study of chemical reactions.

Environmental interest

Fate, transport, and toxicity of related compounds
1-Methoxy-9H-fluorene is of interest in the field of environmental science, as fluorenes have been identified as environmental pollutants. Ongoing research is focused on understanding the fate, transport, and toxicity of 1-methoxy-9H-fluorene and related compounds in the environment.

Upstream product

• 6344-61-2 9H-fluoren-1-ol 
• 77-78-1 dimethyl sulfate 
• 6344-63-4 1-aminofluorene 
• 6276-03-5 9H-fluorene-1-carboxylic acid 
• 55341-64-5 9H-fluorene-1-carboxyl chloride 
• 855623-83-5 fluoren-1-yl isocyanate 
• 88909-93-7 fluorene-1-carbonyl azide 
• 10365-98-7 3-methoxyphenylboronic acid 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 
• 611-17-6 1-bromomethyl-2-chlorobenzene 
• 6630-33-7 ortho-bromobenzaldehyde 
• 578-57-4 2-bromoanisole 
• 1284451-83-7 C₁₄H₁₃BrO₂ 
• 1287721-19-0 1-bromo-2-(2-methoxybenzyl)benzene 

Relevant articles and documents

Aryl or heteroaryl methoxylation reaction method

The invention discloses an aryl or heteroaryl methoxylation reaction method. The method comprises the following steps: preparing a substrate. The coupling agent, ligand, solvent, catalyst and base are mixed homogeneously in an inert gas to give the aryl or heteroaryl methoxy compounds. Compared with a methoxylation reaction method in the prior art, the method has the advantages that the reaction system conditions are mild, the usage amount of the catalyst and the ligand is low to 5% of the amount of the substrate material, and the catalytic efficiency is improved. The method has better compatibility to different substrate expansion and discovery of aryl halides or heteroaryl halides with different functional groups. The yield of aryl or heteroaryl methoxy compounds prepared by the method disclosed by the invention is 36% - 89%.

Palladium-Catalyzed Formal [4 + 1] Annulation via Metal Carbene Migratory Insertion and C(sp2)-H Bond Functionalization

A highly efficient and operationally simple palladium-catalyzed formal [4 + 1] annulation reaction has been developed. The reaction is featured by the formation of two different C-C bonds on a carbenic center. It represents a concise method for the synthesis of a wide range of polycyclic aromatic hydrocarbons (PAHs) and 1H-indenes with easily available (trimethylsilyl)diazomethane as the carbene source. Metal carbene migratory insertion and C(sp2)-H bond activation are proposed as the key steps in this transformation. The reaction further demonstrates the versatility of the carbene-based coupling in combination with various transition-metal-catalyzed transformations.

Halogen-Adjusted Chemoselective Synthesis of Fluorene Derivatives with Position-Controlled Substituents

Fluorenes have been synthesized through an efficient novel Pd-catalyzed tandem cross-coupling reaction; these substrates are fascinating building blocks found in organic photoelectric materials. The position of the substituent on fluorenes could be conveniently tuned by changing the halogen in the ortho-halobenzyl bromide substrates when coupled with various arylboronic acids. This newly developed synthetic approach could achieve the potential diversity in fluorene-based molecular architectures.