26107-80-2

Basic information

• Product Name: METHYL 3,5-BIS(TRIFLUOROMETHYL)BENZOATE
• Synonyms: RARECHEM AL BF 0207;BUTTPARK 89\07-68;METHYL 3,5-DI(TRIFLUOROMETHYL)BENZOATE;METHYL 3,5-BIS(TRIFLUOROMETHYL)BENZOATE;3,5-BIS(TRIFLUOROMETHYL)BENZOIC ACID METHYL ESTER;Methyl 3,5-bis(trifluoromethyl)benzoate 98%;Methyl3,5-bis(trifluoromethyl)benzoate98%;Methyl 3,5-bis(trifluoromethyl)
• CAS NO: 26107-80-2
• Molecular Formula: C₁₀H₆F₆O₂
• Molecular Weight: 272.14
• Product Categories: Benzoic acid
• Mol File: 26107-80-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 85 °C
• Flash Point: 85-87°C/15mm
• Appearance: /
• Density: 1.400±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.217mmHg at 25°C
• Refractive Index: 1.408
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: METHYL 3,5-BIS(TRIFLUOROMETHYL)BENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 3,5-BIS(TRIFLUOROMETHYL)BENZOATE(26107-80-2)
• EPA Substance Registry System: METHYL 3,5-BIS(TRIFLUOROMETHYL)BENZOATE(26107-80-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 26107-80-2(Hazardous Substances Data)

Usage

General Description

Methyl 3,5-bis(trifluoromethyl)benzoate is a chemical compound with the molecular formula C10H6F6O2. It is a ester derivative of benzoic acid, which is commonly used in the production of pharmaceuticals, agrochemicals, and fragrances. METHYL 3,5-BIS(TRIFLUOROMETHYL)BENZOATE is characterized by its highly electronegative trifluoromethyl groups, which makes it useful in various organic synthesis reactions. It is also known for its high thermal stability and resistance to oxidation. Additionally, it is used as a building block in the preparation of novel materials and pharmaceutical intermediates due to its unique properties.

InChI:InChI=1/C10H6F6O2/c1-18-8(17)5-2-6(9(11,12)13)4-7(3-5)10(14,15)16/h2-4H,1H3

Upstream product

• 67-56-1 methanol 
• 401-96-7 3,5-bis(trifluoromethyl)benzoyl fluoride 
• 201230-82-2 carbon monoxide 
• 328-70-1 3,6-bis(trifluoromethyl)bromobenzene 
• 725-89-3 3,5-bistrifluoromethylbenzoic acid 

Downstream Products

• 167853-52-3 [2-(3,5-Bis-trifluoromethyl-phenyl)-2-oxo-ethyl]-phosphonic acid dimethyl ester 
• 167853-54-5 4-[3-(3,5-Bis-trifluoromethyl-phenyl)-3-oxo-propyl]-4-phenyl-piperidine-1-carboxylic acid tert-butyl ester 
• 167853-55-6 4-[3-(3,5-Bis-trifluoromethyl-phenyl)-3-hydroxy-propyl]-4-phenyl-piperidine-1-carboxylic acid tert-butyl ester 
• 334477-34-8 C₁₅H₁₁F₆NO₂ 
• 26107-82-4 3,5-bis-(trifluoromethyl)benzoic acid hydrazide 
• 32707-89-4 3,5-bis(trifluoromethyl)benzenemethanol 

Relevant articles and documents

AMINO ALCOHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF

The present invention belongs to the field of medicine, and specifically discloses an amino alcohol derivative represented by Formula I, a pharmaceutically acceptable salt, solvate, polymorph or prodrug thereof. In addition, the present invention also discloses a pharmaceutical composition comprising the above substances, and a use of the substance in the preparation of a medicament for the prevention and treatment of an immune inflammatory disease, or a disease or condition associated with immunological competence such as multiple sclerosis, ALS, CIDP, systemic lupus erythematosus, rheumatoid arthritis, ulcerative colitis, psoriasis, polymyositis, etc.

The production of the carboxylic acid (by machine translation)

PROBLEM TO BE SOLVED: carbon monoxide which is a toxic gas Nonstoichiometrically controlling environmentally safe and efficient reaction can be done in a continuous-flow system [...] reaction using a transition metal catalyst. SOLUTION: a continuous-flow system, carbon monoxide, eq. (1) R-X (in the formula, R is (C 1-C 10) aryl group, X is a halogen atom or OSO 2 CF 3. ) Compound, a transition metal catalyst, ligand, dissolved in a solvent and a base are uniformly mixed in the retention unit soln. by reaction, eq. (2): RCO-Z (in the formula, R and the p.then, Z is hydroxyl or the l ) Represented by a safe and environmentally friendly calbonyl compd.. Selected drawing: no (by machine translation)