261506-24-5 Usage
Description
(7a,17b)-7-7-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]-estra-1,3,5(10)-triene-3,17-diol 17-acetate, also known as Fulvestrant 17-Acetate, is a synthetic steroidal estrogen antagonist used in the pharmaceutical industry. It is characterized by its complex chemical structure, which includes a pentafluoropentylsulfinyl group attached to a nonyl chain, and an acetate group at the 17-position. (7a,17b)-7-7-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]-estra-1,3,5(10)-triene-3,17-diol 17-acetate plays a crucial role in the synthesis of Fulvestrant 3-β-D-Glucuronide (F862510), a metabolite of Fulvestrant (F862500).
Uses
Used in Pharmaceutical Industry:
Fulvestrant 17-Acetate is used as an intermediate in the synthesis of Fulvestrant 3-β-D-Glucuronide (F862510) for the development of pharmaceutical drugs. The compound is essential in creating a metabolite of Fulvestrant (F862500), which is a steroidal estrogen antagonist used in the treatment of hormone receptor-positive metastatic breast cancer.
Used in Cancer Treatment:
Fulvestrant 17-Acetate contributes to the development of cancer treatment options by being a part of the synthesis process for Fulvestrant 3-β-D-Glucuronide (F862510). This metabolite is derived from Fulvestrant (F862500), a drug that has demonstrated efficacy in treating hormone receptor-positive metastatic breast cancer by competitively binding to estrogen receptors, thereby blocking the effects of estrogen and inhibiting cancer cell growth.
Check Digit Verification of cas no
The CAS Registry Mumber 261506-24-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,1,5,0 and 6 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 261506-24:
(8*2)+(7*6)+(6*1)+(5*5)+(4*0)+(3*6)+(2*2)+(1*4)=115
115 % 10 = 5
So 261506-24-5 is a valid CAS Registry Number.
261506-24-5Relevant articles and documents
Process for the preparation of 7alpha-alkylated 19-norsteroids
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Page/Page column 26, (2008/06/13)
Processes useful in the preparation of pharmaceutical compounds such as fulvestrant and processes for the preparation of fulvestrant.
