26167-45-3 Usage
Description
1-Benzo[b]thiophen-3-yl-2-bromoethan-1-one is a chemical compound belonging to the class of thiazole analogs. It is characterized by its gray solid appearance and is known for its selective inhibition of cyclooxygenase-2 (COX-2), making it a potential candidate for the development of anti-inflammatory and analgesic drugs.
Uses
Used in Pharmaceutical Industry:
1-Benzo[b]thiophen-3-yl-2-bromoethan-1-one is used as a selective COX-2 inhibitor for the development of anti-inflammatory and analgesic drugs. Its application in this industry is due to its ability to inhibit the COX-2 enzyme, which is involved in the production of prostaglandins that cause inflammation and pain. By selectively targeting COX-2, this compound may offer a more targeted approach to treating inflammation and pain with potentially fewer side effects compared to non-selective COX inhibitors.
Additionally, due to its chemical properties and structural similarity to indomethacin, a well-known non-steroidal anti-inflammatory drug (NSAID), 1-Benzo[b]thiophen-3-yl-2-bromoethan-1-one may also be used in the research and development of new NSAIDs with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 26167-45-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,1,6 and 7 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 26167-45:
(7*2)+(6*6)+(5*1)+(4*6)+(3*7)+(2*4)+(1*5)=113
113 % 10 = 3
So 26167-45-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H7BrOS/c11-5-9(12)8-6-13-10-4-2-1-3-7(8)10/h1-4,6H,5H2
26167-45-3Relevant articles and documents
COMPOUNDS FOR THE TREATMENT OF PARAMOXYVIRUS VIRAL INFECTIONS
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Paragraph 0548, (2014/03/25)
Disclosed herein are new antiviral compounds, together with pharmaceutical compositions that include one or more antiviral compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a paramyxovirus viral infection with one or more small molecule compounds. Examples of paramyxovirus infection include an infection caused by human respiratory syncytial virus (RSV).
Baker's yeast-mediated synthesis of (R)- and (S)-heteroaryl-ethane-1,2-diols
Podea, Paula Veronica,Paizs, Csaba,Tosa, Monica Ioana,Irimie, Florin Dan
, p. 1959 - 1964 (2008/12/22)
Baker's yeast-mediated enantioselective bioreduction of 1-(heteroaryl)-2-hydroxyethanones and 2-acetoxy-1-(hetero-aryl)ethanones was used for the enantioselective synthesis of both (R)- and (S)-benzofuranyl-, benzo[b]thiophenyl- and benzo[d]thiazolyl-ethane-1,2-diols.
Condensed thiazole derivatives, having 5-HT receptor affinity
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, (2008/06/13)
Compounds of formula I STR1 in which A is S(O) p or O;p is 0, 1 or 2;g is 0, 1, 2, 3, or 4;n is 2 or 3; andR 1, R 2, R 3, R 4 and R 5 are optional substituents have utility in the treatment of central nervous system disorders, for example depression, anxiety, psychoses (for example schizophrenia), tardive dyskinesia, obesity, drug addiction, drug abuse, cognitive disorders, Alzheimer''s disease, senile dementia, cerebral ischemia, obsessive-compulsive behavior, panic attacks, social phobias, eating disorders and anorexia, non-insulin dependent diabetes mellitus, hyperglycemia, and stress.
