261728-61-4 Usage
Description
D-[1,2-13C2]GLUCOSE, also known as D-Glucose-1,2-13C2, is a labeled monosaccharide that is present in plants. It may exist in an open chain or cyclic conformation when in solution. This simple sugar plays a crucial role in photosynthesis and provides the energy necessary for cellular respiration. D-[1,2-13C2]GLUCOSE is characterized by the presence of two 13C isotopes at the first and second carbon positions, which makes it useful for various applications in different fields.
Uses
Used in Metabolic Research:
D-[1,2-13C2]GLUCOSE is used as a research tool for studying various metabolic processes. Its application is particularly valuable in the enzymic synthesis of cyclohexyl-α and β-D-glucosides, which are important for understanding the biochemical pathways involving glucose metabolism.
Used in Medical Diagnostics:
In the medical field, D-[1,2-13C2]GLUCOSE is used as a diagnostic tool for the detection of type 2 diabetes mellitus. By analyzing blood-glucose levels, this labeled glucose can help identify the presence of the disease and monitor the effectiveness of treatment strategies.
Additionally, D-[1,2-13C2]GLUCOSE has potential applications in the detection of other diseases, such as Huntington's disease, through the analysis of blood-glucose levels in type 1 diabetes mellitus patients.
Used in Pharmaceutical Industry:
D-[1,2-13C2]GLUCOSE can be utilized in the development of new drugs and therapies targeting glucose metabolism-related disorders. Its unique isotopic labeling allows for the tracking of glucose metabolism in the body, which can lead to a better understanding of the underlying mechanisms of these diseases and the development of more effective treatments.
Used in Agricultural Research:
In agriculture, D-[1,2-13C2]GLUCOSE can be employed to study the role of glucose in plant growth and development. This knowledge can be applied to improve crop yields and understand the metabolic pathways involved in plant responses to various environmental stresses.
Check Digit Verification of cas no
The CAS Registry Mumber 261728-61-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,1,7,2 and 8 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 261728-61:
(8*2)+(7*6)+(6*1)+(5*7)+(4*2)+(3*8)+(2*6)+(1*1)=144
144 % 10 = 4
So 261728-61-4 is a valid CAS Registry Number.
261728-61-4Relevant articles and documents
Biosynthesis of glucose-d-13C6 from Hansenula polymorpha and methanol-13C
Liu, Zhan-Feng,Ren, Zheng,Xu, Da-Gang,Li, Liang-Jun
experimental part, p. 44 - 47 (2012/06/29)
A simple and effective method for synthesis of glucose-d- 13C6 by fermentation using the methylotrophic yeast Hansenula polymorpha with 99% abundance methanol-13C is described. Using methanol-13C as a sole source of carbon, H. polymorpha can accumulate large amounts of α,α-trehalose-13C 12 under unfavourable growth conditions; the trehalose can then be hydrolysed to give glucose-d-13C6 with 98.5% abundance 13C.
