261951-78-4 Usage
General Description
2-Fluoro-5-(trifluoromethyl)anisole is a chemical compound with the molecular formula C8H6F4O. It is a colorless, flammable liquid with a faint aromatic odor. 2-FLUORO-5-(TRIFLUOROMETHYL)ANISOLE is often used as an intermediate in the production of pharmaceuticals, agrochemicals, and other fine chemicals. It is also used as a reagent in organic synthesis and as a solvent in various chemical processes. Additionally, it is known for its mild anesthetic properties and has potential applications in the field of medicine. However, it is important to handle this chemical with caution, as it may present health hazards if not used properly.
Check Digit Verification of cas no
The CAS Registry Mumber 261951-78-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,1,9,5 and 1 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 261951-78:
(8*2)+(7*6)+(6*1)+(5*9)+(4*5)+(3*1)+(2*7)+(1*8)=154
154 % 10 = 4
So 261951-78-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H6F4O/c1-13-7-4-5(8(10,11)12)2-3-6(7)9/h2-4H,1H3
261951-78-4Relevant articles and documents
Preparation of Indolenines via Nucleophilic Aromatic Substitution
Huber, Florian,Roesslein, Joel,Gademann, Karl
supporting information, p. 2560 - 2564 (2019/03/19)
An unusual aromatic substitution to access indolenines is described. 2-(2-Methoxyphenyl)acetonitrile derivatives are reacted with various alkyl and aryl Li reagents to furnish the corresponding indolenine products, constituents of natural products, and cyanine dyes such as indocyanine green. This new method was used to synthesize 41 indolenines with large functional group tolerance, and selected examples were further converted to the corresponding indolenine dyes. Key experiments provide insight into the mechanism of this nucleophilic aromatic substitution.