2620-81-7

Basic information

• Product Name: 2-(4-METHOXYPHENYL)-1H-BENZIMIDAZOLE
• Synonyms: 2-(4-METHOXYPHENYL)-1H-BENZIMIDAZOLE;TIMTEC-BB SBB000638;2-(4-METHOXYPHENYL)-1H-BENZO[D]IMIDAZOLE;OTAVA-BB 1056467;1H-BenziMidazole, 2-(4-Methoxyphenyl)-BenziMidazole, 2-(p-Methoxyphenyl)- (6CI,7CI,8CI);2-(4-Methoxyphenyl)benziMidazole, 95%;2-(4-Methoxyphenyl)-1H-benzoimidazole
• CAS NO: 2620-81-7
• Molecular Formula: C₁₄H₁₂N₂O
• Molecular Weight: 224.26
• Mol File: 2620-81-7.mol
• Article Data: 306

Chemical Properties

• Melting Point: 228-230 °C
• Boiling Point: 428.2°C at 760 mmHg
• Flash Point: 154.4°C
• Appearance: /
• Density: 1.216g/cm³
• Vapor Pressure: 1.55E-07mmHg at 25°C
• Refractive Index: 1.657
• PKA: 11.49±0.10(Predicted)
• CAS DataBase Reference: 2-(4-METHOXYPHENYL)-1H-BENZIMIDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-METHOXYPHENYL)-1H-BENZIMIDAZOLE(2620-81-7)
• EPA Substance Registry System: 2-(4-METHOXYPHENYL)-1H-BENZIMIDAZOLE(2620-81-7)

Safety Data

• Hazardous Substances Data: 2620-81-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H12N2O/c1-17-11-8-6-10(7-9-11)14-15-12-4-2-3-5-13(12)16-14/h2-9H,1H3,(H,15,16)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 95-54-5 1,2-diamino-benzene 
• 100-09-4 4-methoxybenzoic acid 
• 4414-88-4 1H-benzimidazol-2-acetonitrile 
• 2826-26-8 2-(4-methoxyphenylmethylene)malononitrile 
• 75220-77-8 2-(4-methoxyphenyl)-4-phenyl-2,3-dihydro-1H-benzo[b][1,4]diazepine 
• 103517-57-3 N₁-(4-methoxybenzoyl)-1,2-benzenediamine 
• 79613-20-0 2-[(2'-p-anisyl-1'-cyano)ethen-1'-yl]1H-benzimidazole 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 201230-82-2 carbon monoxide 
• 696-62-8 para-iodoanisole 
• 3179-10-0 (E)-1-methoxy-4-(2-nitrovinyl)benzene 
• 126336-72-9 5-{[1-(4-Methoxy-phenyl)-1-methylsulfanyl-meth-(Z)-ylidene]-amino}-1-methyl-3,4-dihydro-2H-pyrrolium; iodide 
• 31709-47-4 3-(4-methoxyphenyl)isoxazol-5(4H)-one 

Downstream Products

• 100726-37-2 2-(4-methoxy-phenyl)-1-nitroso-1H-benzimidazole 
• 872604-78-9 [2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]-acetic acid ethyl ester 
• 332171-55-8 1-ferrocenylmethyl-2-(4-methoxyphenyl)-1H-benzimidazole 
• 1240736-60-0 2-(4-methoxyphenyl)-1-[4-(2-piperidin-1-ylethoxy)benzyl]-1H-benzimidazole 
• 1356545-26-0 benzoic acid (E)-1-(benzylbenzyloxycarbonylamino)-2-phenylvinyl ester 
• 1081111-23-0 2-(4-methoxyphenyl)-1-{3-[4-(3-acetylaminophenyl)piperidin-1-yl]propyl}-1H-benzimidazole 
• 1174039-97-4 3-methyl-6-phenylbenzo[4,5]imidazo[2,1-a]isoquinoline 
• 1417818-94-0 3-methoxy-6-phenylbenzo[4,5]imidazo[2,1-a]isoquinoline 
• 1238292-62-0 3-methoxy-5,6-diphenylbenzo[4,5]imidazo[2,1-a]isoquinoline 
• 1447946-67-9 C₂₅H₂₀N₂O₃ 
• 1609007-36-4 (E)-1-(2-(4-methoxyphenyl)-1H-benzo[d]imidazol-1-yl)-3-phenylprop-2-en-1-one 

Relevant articles and documents

Vibrational spectrum and assignments of 2-(4-methoxyphenyl)-1H-benzo[d]imidazole by ab initio Hartree-Fock and density functional methods

The room temperature attenuated total reflection Fourier transform infrared spectrum of the 2-(4-methoxyphenyl)-1H-benzo[d]imidazole has been recorded with diamond/ZnSe prism. The conformational behaviour, structural stability of optimized geometry, frequ

[Diaquo{bis(p-hydroxybenzoato-κ1O1)}(1-methylimidazole- κ1N1)}copper(II)]: Synthesis, crystal structure, catalytic activity and DFT study

Metal-organic hybrid complexes often exhibit large surface area, pore volume, fascinating structures and potential applications including catalytic applications. Hence a new metal-organic hybrid complex [Diaquo{bis(p-hydroxybenzoato-κ1O1)}(1-methylimidazole- κ1N1)}copper(II)] was synthesized using conventional method. Physico-chemical characterization of the complex was performed with FTIR spectroscopy, single crystal X-ray diffraction, TGA, EPR and FESEM. Single crystal X-ray diffraction study suggests it to be three dimensional with space group P212121 (orthorhombic). The crystal achieves its three-dimensional structure and stability through extensive intermolecular hydrogen bonding. Hirshfeld surface analysis, catalytic activity and DFT study of the complex was also performed. The synthesized complex acts as good catalyst in benzimidazole synthesis with good recyclability as catalyst up to 5th run.

Preparation method 2 -substituted benzimidazole derivative

The invention belongs to the field of fine chemical product production, and particularly relates to 2 -substituted benzimidazole derivative preparation method which comprises the following steps: (1) taking O-phenylenediamine and aldehyde as raw materials, carrying out catalytic condensation, cyclization and oxidation reaction in a eutectic solvent. (2) Water is added to the reaction system, the separated product is filtered, and the eutectic solvent is recycled. (3) After recrystallization, a target product is obtained. The method has the advantages of simple operation process, easily available raw materials, low cost, high purity of the target product and no catalyst participation, can effectively prevent isomer formation, and is beneficial to large-scale production.

Reusable nano-zirconia-catalyzed synthesis of benzimidazoles and their antibacterial and antifungal activities

In this article, a zirconia-based nano-catalyst (Nano-ZrO2 ), with intermolecular C-N bond formation for the synthesis of various benzimidazole-fused heterocycles in a concise method is reported. The robustness of this reaction is demonstrated