262296-00-4

Basic information

• Product Name: 2-(4-MORPHOLINYL)-PYRIDINE-4-CARBOXYLIC ACID METHYL ESTER
• Synonyms: 2-(4-MORPHOLINYL)-PYRIDINE-4-CARBOXYLIC ACID METHYL ESTER
• CAS NO: 262296-00-4
• Molecular Formula: C11H14N2O3
• Molecular Weight: 222.24
• Mol File: 262296-00-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 391.8°Cat760mmHg
• Flash Point: 190.7°C
• Appearance: /
• Density: 1.208g/cm³
• Vapor Pressure: 2.41E-06mmHg at 25°C
• Refractive Index: 1.542
• PKA: 3.41±0.10(Predicted)
• CAS DataBase Reference: 2-(4-MORPHOLINYL)-PYRIDINE-4-CARBOXYLIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-MORPHOLINYL)-PYRIDINE-4-CARBOXYLIC ACID METHYL ESTER(262296-00-4)
• EPA Substance Registry System: 2-(4-MORPHOLINYL)-PYRIDINE-4-CARBOXYLIC ACID METHYL ESTER(262296-00-4)

Safety Data

• Hazardous Substances Data: 262296-00-4(Hazardous Substances Data)

Usage

Structure

Methyl ester of pyridine-4-carboxylic acid with a morpholine ring attached to the 2-position

Uses

Intermediate in the synthesis of pharmaceuticals and agrochemicals, potential applications in medicine, agriculture, and material science

Physical form

White to off-white solid

Molecular weight

230.252 g/mol

Solubility

Sparingly soluble in water

Safety precautions

Potential health hazards, proper handling and storage required

InChI:InChI=1/C11H14N2O3/c1-15-11(14)9-2-3-12-10(8-9)13-4-6-16-7-5-13/h2-3,8H,4-7H2,1H3

Upstream product

• 110-91-8 morpholine 
• 6313-54-8 2-chloroisonicotinic acid, 
• 58481-11-1 methyl 2-chloroisonicotinate 

Relevant articles and documents

2-AMINOQUINAZOLINE DERIVATIVES

2-Aminoquinazoline derivatives represented by the general formula (I) or pharmacologically acceptable salts thereof: (I) wherein R1 and R2 are each independently hydrogen, substituted or unsubstituted lower alkyl, or the like; X is a bond or CR7aR7b (wherein R7a and R7b are each independently hydrogen or the like); when X is a bond, R3 is substituted or unsubstituted aryl or a substituted or unsubstituted aromatic heterocyclic group, while when X is CR7aR7b, R3 is substituted or unsubstituted lower alkoxy, substituted or unsubstituted aryl, or the like; R4 is hydrogen, hydroxy, substituted or unsubstituted lower alkoxy, or the like; and R5 is hydrogen, substituted or unsubstituted aryl, or the like.

CYANOPHENYL DERIVATIVES

This application relates to a piperazino-substituted novel cyanophenyl derivative in which a substituted carbamoyl or substituted sulfamoyl group having an aryl, heterocyclic or the like group that may have a substituent group is bonded to one nitrogen atom on the piperazine ring. The compound of this application has an anti-androgen action and is useful in preventing or treating prostatic cancer, benign prostatic hyperplasia and the like diseases.