262299-32-1

Basic information

• Product Name: piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-[4-(2-morpholin-4-yl-2-oxo-ethoxycarbonyl)-phenyl] ester
• Synonyms: piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-[4-(2-morpholin-4-yl-2-oxo-ethoxycarbonyl)-phenyl] ester
• CAS NO: 262299-32-1
• Molecular Weight: 476.527
• Mol File: 262299-32-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-[4-(2-morpholin-4-yl-2-oxo-ethoxycarbonyl)-phenyl] ester(CAS DataBase Reference)
• NIST Chemistry Reference: piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-[4-(2-morpholin-4-yl-2-oxo-ethoxycarbonyl)-phenyl] ester(262299-32-1)
• EPA Substance Registry System: piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-[4-(2-morpholin-4-yl-2-oxo-ethoxycarbonyl)-phenyl] ester(262299-32-1)

Safety Data

• Hazardous Substances Data: 262299-32-1(Hazardous Substances Data)

Upstream product

• 84358-13-4 N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid 
• 262298-70-4 4-hydroxy-benzoic acid 2-morpholin-4-yl-2-oxo-ethyl ester 
• 99-96-7 4-hydroxy-benzoic acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1440-61-5 N-chloroacetylmorpholine 
• 498-94-2 isonipecotic acid 

Relevant articles and documents

Synthesis and structure-activity relationship study of the new set of trypsin-like proteinase inhibitors

A new set of 25 trypsin-like proteinase inhibitors was prepared and the inhibiting activity on trypsin, thrombin, plasmin and urokinase was measured. The structure-activity relationship is discussed. High inhibiting activities were observed in 4-guanidinobenzoic acid esters only. The replacement of this moiety for N-formamidinyl-isonipecotic acid or an arginine moiety caused almost total loss of the activity. In the series of 4-guanidinobenzoic acid esters, any important influence of the ester-groups reactivity was observed. The trypsin-thrombin selectivity in the compounds with the guanidine-remote carboxylic function was also observed.