263339-24-8

Basic information

• Product Name: 4-(4-AMINOBENZYL)-1LAMBDA6,4-THIAZINANE-1,1-DIONE
• Synonyms: 4-(4-AMINOBENZYL)-1LAMBDA6,4-THIAZINANE-1,1-DIONE;4-(4'-Aminobenzyl)thiomorpholine 1,1-dioxide;4-[(1,1-DIOXIDOTHIOMORPHOLIN-4-YL)METHYL]ANILINE;(4-Aminobenzyl)thiomorpholine 1,1-dioxide;4-[(1,1-Dioxidothiomorpholin-4-yl)methyl]aniline90%
• CAS NO: 263339-24-8
• Molecular Formula: C₁₁H₁₆N₂O₂S
• Molecular Weight: 240.32
• Mol File: 263339-24-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 156 °C
• Boiling Point: 465.3°Cat760mmHg
• Flash Point: 235.2°C
• Appearance: /
• Density: 1.301g/cm³
• Vapor Pressure: 7.8E-09mmHg at 25°C
• Refractive Index: 1.611
• PKA: 5.69±0.20(Predicted)
• CAS DataBase Reference: 4-(4-AMINOBENZYL)-1LAMBDA6,4-THIAZINANE-1,1-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-AMINOBENZYL)-1LAMBDA6,4-THIAZINANE-1,1-DIONE(263339-24-8)
• EPA Substance Registry System: 4-(4-AMINOBENZYL)-1LAMBDA6,4-THIAZINANE-1,1-DIONE(263339-24-8)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39
• RIDADR: 3259
• Hazardous Substances Data: 263339-24-8(Hazardous Substances Data)

Usage

General Description

4-(4-aminobenzyl)-1LAMBDA6,4-thiazinane-1,1-dione, also known as amiodarone, is a medication used to treat and prevent certain types of serious, life-threatening ventricular arrhythmias. It belongs to a class of drugs called antiarrhythmics, which work by stabilizing the heart's electrical activity and reducing abnormal rhythms. This medication is typically administered orally or intravenously and has a long half-life, allowing for once-daily dosing. Amiodarone is also known for its potential for serious side effects, including lung, liver, and thyroid toxicity, and requires close monitoring and regular follow-up with healthcare providers. Despite its potential risks, amiodarone remains an important medication for managing specific heart rhythm disorders.

InChI:InChI=1/C11H16N2O2S/c12-11-3-1-10(2-4-11)9-13-5-7-16(14,15)8-6-13/h1-4H,5-9,12H2

Upstream product

• 77-77-0 Divinyl sulfone 
• 4403-71-8 (4-aminomethyl)aniline 

Downstream Products

• 929891-59-8 3-bromo-N-[4-(1,1-dioxo-1λ6-thiomorpholin-4-ylmethyl)-phenyl]-4-methoxy-benzamide 
• 929891-01-0 4'-[4-(1,1-dioxo-1λ6-thiomorpholin-4-ylmethyl)-phenylcarbamoyl]-6-methyl-biphenyl-3-carboxylic acid methyl ester 
• 929891-27-0 5'-cyano-2'-methyl-biphenyl-4-carboxylic acid [4-(1,1-dioxo-1λ6-thiomorpholin-4-ylmethyl)-phenyl]-amide 
• 1056635-99-4 N-(cyanomethyl)-4-[2-((4-[(1,1-dioxo-1λ6,4-thiomorpholin-4-yl)methyl]phenyl)amino)pyrimidin-4-yl]benzamide 
• 1132825-60-5 5-bromo-thiophene-2-carboxylicacid[4-(1,1-dioxo-1lambda-*6*-thiomorpholin-4-ylmethyl)-phenyl]-amide 
• 1132825-13-8 4-[2-methyl-5-(4-morpholin-4-yl-phenylcarbamoyl)-phenyl]-piperazine-1-carboxylic acid [4-(1,1-dioxo-1lambda-*6*-thiomorpholin-4-ylmethyl)-phenyl]-amide 
• 1132824-77-1 5-[2-methyl-5-(4-morpholin-4-yl-phenylcarbamoyl)-phenyl]-furan-2-carboxylic acid [4-(1.1-dioxo-1lambda-*6*-thiomorpholin-4-ylmethyl)-phenyl]-amide 
• 1197010-60-8 C₂₂H₂₅N₅O₄S₂ 
• 1240501-34-1 N-[4-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide 

Relevant articles and documents

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