263364-71-2

Basic information

• Product Name: 6-methoxy-3-(4-methoxyphenyl)-2H-chromen-2-one
• Synonyms: 6-methoxy-3-(4-methoxyphenyl)-2H-chromen-2-one
• CAS NO: 263364-71-2
• Molecular Weight: 282.296
• Mol File: 263364-71-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 6-methoxy-3-(4-methoxyphenyl)-2H-chromen-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methoxy-3-(4-methoxyphenyl)-2H-chromen-2-one(263364-71-2)
• EPA Substance Registry System: 6-methoxy-3-(4-methoxyphenyl)-2H-chromen-2-one(263364-71-2)

Safety Data

• Hazardous Substances Data: 263364-71-2(Hazardous Substances Data)

Upstream product

• 672-13-9 2-hydroxy-5-methoxybenzaldehyde 
• 104-01-8 4-Methoxyphenylacetic acid 
• 123331-31-7 1-(1H-imidazol-1-yl)-2-(4-methoxyphenyl)ethan-1-one 

Relevant articles and documents

Facile one-pot synthetic access to libraries of diversely substituted 3-aryl (Alkyl)-coumarins using ionic liquid (IL) or conventional base/solvent, and an IL-mediated approach to novel coumarin-bearing diaryl-ethynes

The in-situ formed carbonylimidazole derivatives of Ar(alkyl)-CH2COOH react at r.t. with substituted salicylaldehydes in [BMIM][PF6] or [BMIM][BF4] as solvent, and [PAIM][NTf2] as basic-IL, to produce libraries of 3-aryl(alkyl)coumarins. Whereas these reactions can also be performed with similar efficiency in THF by employing DBU, the IL approach offers easier work-up and recycling of the IL solvent. An IL-mediated approach to the synthesis of novel coumarin-bearing diaryl-ethynes by the Sonogshira reaction is also reported, and the potential for recycling/reuse of the IL solvent is shown.

Ultrasound-Assisted Solvent-Free Parallel Synthesis of 3-Arylcoumarins Using N-Acylbenzotriazoles

An ultrasound-assisted one-pot acylation/cyclization reaction between N-acylbenzotriazoles and 2-hydroxybenzaldehydes has been developed for the synthesis of substituted 3-arylcoumarins. Using ultrasound not only allows rapid and clean conversion but also simplifies experimental setup and parallel workup leading to rapid generation of 3-arylcoumarin libraries under mild, solvent-free, and chromatography-free conditions.