2635-10-1 Usage
Description
METHIOCARB SULFOXIDE, also known as a carbamate ester, is a compound derived from the formal condensation of the phenolic group of 3,5-dimethyl-4-(methylsulfinyl)phenol with the carboxy group of methylcarbamic acid. It is a metabolite of the pesticide methiocarb and possesses significant importance in the field of chemistry and environmental science.
Uses
Since the provided materials do not explicitly mention the uses of METHIOCARB SULFOXIDE, we can infer potential applications based on its properties and origin. Here are some possible uses:
Used in Chemical Research:
METHIOCARB SULFOXIDE is used as a research compound for studying the properties and behavior of carbamate esters and their metabolites in various chemical reactions and processes.
Used in Environmental Science:
METHIOCARB SULFOXIDE is used as an analytical compound for monitoring and assessing the presence of methiocarb and its metabolites in the environment, particularly in soil and water samples.
Used in Pesticide Analysis:
METHIOCARB SULFOXIDE is used as a reference compound in the development and validation of analytical methods for the detection and quantification of methiocarb and its metabolites in agricultural products and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 2635-10-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,6,3 and 5 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2635-10:
(6*2)+(5*6)+(4*3)+(3*5)+(2*1)+(1*0)=71
71 % 10 = 1
So 2635-10-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H15NO3S/c1-7-5-9(15-11(13)12-3)6-8(2)10(7)16(4)14/h5-6H,1-4H3,(H,12,13)
2635-10-1Relevant articles and documents
Stereoselective sulfoxidation of the pesticide methiocarb by flavin-containing monooxygenase and cytochrome P450-dependent monooxygenases of rat liver microsomes. Anticholinesterase activity of the two sulfoxide enantiomers.
Buronfosse,Moroni,Benoit,Riviere
, p. 179 - 189 (1995)
Evidence based on thermal lability and enzyme inhibition data suggests that the sulfoxidation of methiocarb (an N-methylcarbamate insecticide) by rat liver microsomes is catalyzed by flavin-containing monooxygenase(s) (FMO) and by cytochrome(s) P450 (P450). In control rats, the relative proportion is ca. 50% P450:50% FMO. Stereoselective formation of methiocarb sulfoxide from the corresponding sulfide has also been examined to compare the enantioselectivity of the two different enzyme systems. Only the FMO-dependent sulfoxidation presents a high stereoselectivity with an enantiomeric excess of 88% in favor of the (A)-enantiomer. Pretreatment of rats with different P450 inducers such as phenobarbital, 3-methylcholanthrene, dexamethasone, and pyrazole did not affect, or decreased, the rate of methiocarb sulfoxidation. Stereoselectivity of the reaction was modified, mainly because of changes in the relative involvement of FMO and P450 in sulfoxidase activity in pretreated animals. The acetylcholinesterase inhibition properties of methiocarb and its main metabolites were also investigated. Racemic methiocarb sulfoxide was slightly less inhibitory (Ki = 0.216 microM-1.min-1) than methiocarb, but a 10-fold difference was observed between the bimolecular rate constants found for the two sulfoxides produced (0.054 and 0.502 microM-1.min-1 for the (A) and (B) enantiomers, respectively).