26416-38-6

Basic information

• Product Name: methyl 2-{[(1-methoxy-1-oxo-3-phenylpropan-2-yl)carbamoyl]amino}-3-phenylpropanoate (non-preferred name)
• CAS NO: 26416-38-6
• Molecular Formula: C₂₁H₂₄N₂O₅
• Molecular Weight: 384.4257
• Mol File: 26416-38-6.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 581.6°C at 760 mmHg
• Flash Point: 305.6°C
• Density: 1.197g/cm³
• Vapor Pressure: 1.61E-13mmHg at 25°C
• Refractive Index: 1.557
• CAS DataBase Reference: methyl 2-{[(1-methoxy-1-oxo-3-phenylpropan-2-yl)carbamoyl]amino}-3-phenylpropanoate (non-preferred name)(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-{[(1-methoxy-1-oxo-3-phenylpropan-2-yl)carbamoyl]amino}-3-phenylpropanoate (non-preferred name)(26416-38-6)
• EPA Substance Registry System: methyl 2-{[(1-methoxy-1-oxo-3-phenylpropan-2-yl)carbamoyl]amino}-3-phenylpropanoate (non-preferred name)(26416-38-6)

Safety Data

• Hazardous Substances Data: 26416-38-6(Hazardous Substances Data)

Upstream product

• 17463-57-9 N-(succinimid-1-ylcarbonyl)-L-phenylalanine methyl ester 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 530-62-1 1,1'-carbonyldiimidazole 
• 5070-13-3 bis-(p-nitrophenyl) carbonate 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 142311-87-3 (S)-2-Methylsulfanylcarbonylamino-3-phenyl-propionic acid methyl ester 
• 201230-82-2 carbon monoxide 
• 51987-73-6 (S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid methyl ester 
• 1256930-64-9 (S)-methyl 2-(3-hydroxyureido)-3-phenylpropanoate 
• 63-91-2 L-phenylalanine 
• 40203-94-9 methyl (S)-2-isocyanato-3-phenylpropanoate 
• 124-38-9 carbon dioxide 
• 32315-10-9 bis(trichloromethyl) carbonate 

Downstream Products

• 13589-08-7 (S,S)-N,N'-bis(1-carboxy-2-phenylethyl)urea 
• 96943-03-2 (S)-2-((S)-4-benzyl-2,5-dioxoimidazolidin-1-yl)-3-phenylpropanoic acid 
• 1244610-62-5 (S,S)-N-hydroxy-2-[3-(1-hydroxycarbamoyl-2-phenylethyl)-ureido]-3-phenyl-propionamide 

Relevant articles and documents

Preparation of Carbodiimides with One-Handed Axial Chirality

The axial chirality of carbodiimide was proposed in 1932, but the synthesis of carbodiimide with one-handed axial chirality has not been achieved because of the low barrier of racemization. This work presents a strategy to use a conformationally restrained cyclic structure for creating carbodiimides whose biases of the axial chirality (labeled as SNCN/RNCN) are higher than 100:1, as determined by vibrational circular dichroism spectroscopy and density functional theory calculations.

A One-Pot Synthesis of Symmetrical and Unsymmetrical Dipeptide Ureas

We describe a flexible and high yielding synthesis of 1,3-disubstituted ureas that allows for the construction of both symmetrical and unsymmetrical dipeptide ureas, including easy access to 13C-labelled ureas, from amino acids and carbon dioxide at atmospheric pressure. We describe a flexible and high yielding synthesis of 1,3-disubstituted ureas, that allows for the construction of both symmetrical and unsymmetrical dipeptide ureas, including easy access to 13C labelled ureas, from amino acids and carbon dioxide at atmospheric pressure.

Semicarbazones from N-hydroxyureas and amines: A novel entry in the reactivity of the acyl nitroso group

The condensation of carbamoyl nitroso compounds, obtained by oxidation of N-hydroxyureas, with amines unexpectedly afforded semicarbazones (aka carbamoyl hydrazones). Although the substitution of the nitrosyl moiety might compete to afford the correspondi