2642-37-7 Usage
Description
3-Indoxyl sulfate potassium salt is an uremic toxin that acts as a potent endogenous agonist for the human aryl hydrocarbon receptor (AHR). It is a white to off-white crystalline powder and is considered a sensitive and early biomarker of nephrotoxicity.
Uses
Used in Pharmaceutical Industry:
3-Indoxyl sulfate potassium salt is used as a pharmaceutical agent for the treatment of chronic kidney disease and related conditions. Its ability to act as an AHR agonist makes it a potential therapeutic target for modulating the AHR pathway, which plays a role in various physiological and pathological processes.
Used in Research Applications:
3-Indoxyl sulfate potassium salt is used as a research tool for studying the role of AHR in various biological processes and diseases. It helps researchers understand the molecular mechanisms underlying the AHR pathway and its implications in nephrotoxicity and other conditions.
Used in Diagnostic Applications:
3-Indoxyl sulfate potassium salt is used as a biomarker for the early detection of nephrotoxicity, allowing for timely intervention and management of kidney-related disorders. Its sensitivity as a biomarker makes it a valuable tool in the diagnosis and monitoring of kidney function.
Check Digit Verification of cas no
The CAS Registry Mumber 2642-37-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,6,4 and 2 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2642-37:
(6*2)+(5*6)+(4*4)+(3*2)+(2*3)+(1*7)=77
77 % 10 = 7
So 2642-37-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H7NO4S.K/c10-14(11,12)13-8-5-9-7-4-2-1-3-6(7)8;/h1-5,9H,(H,10,11,12);/q;+1/p-1