264277-40-9

Basic information

• Product Name: [1-(1-benzyl-piperidin-4-ylcarbamoyl)-3-hydroxy-propyl]-carbamic acid tert-butyl ester
• Synonyms: [1-(1-benzyl-piperidin-4-ylcarbamoyl)-3-hydroxy-propyl]-carbamic acid tert-butyl ester
• CAS NO: 264277-40-9
• Molecular Weight: 391.511
• Mol File: 264277-40-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [1-(1-benzyl-piperidin-4-ylcarbamoyl)-3-hydroxy-propyl]-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [1-(1-benzyl-piperidin-4-ylcarbamoyl)-3-hydroxy-propyl]-carbamic acid tert-butyl ester(264277-40-9)
• EPA Substance Registry System: [1-(1-benzyl-piperidin-4-ylcarbamoyl)-3-hydroxy-propyl]-carbamic acid tert-butyl ester(264277-40-9)

Safety Data

• Hazardous Substances Data: 264277-40-9(Hazardous Substances Data)

Upstream product

• 41088-86-2 L-2-(tert-butyloxycarbonylamino)-4-hydroxybutyric acid 
• 40856-59-5 tert-butyl (3S)-2-oxotetrahydrofuran-3-ylcarbamate 

Relevant articles and documents

Efficient synthesis of 1-heterocyclic-3-aminopyrrolidinones

A novel two-step synthesis of optically active 3-aminopyrrolidinones is described. The route allows access to pyrrolidinones with heterocyclic functionality that is incompatible with known methodology, and affords the final products in good to excellent yield and high enantiomeric purity. The Mitsunobu cyclodehydration is shown to be an efficient method for the formation of a variety of γ-lactams. (C) 2000 Published by Elsevier Science Ltd.