264907-65-5

Basic information

• Product Name: 2-(4-bromophenylamino)-3-methylbut-2-enenitrile
• Synonyms: 2-(4-bromophenylamino)-3-methylbut-2-enenitrile
• CAS NO: 264907-65-5
• Molecular Weight: 251.126
• Mol File: 264907-65-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-bromophenylamino)-3-methylbut-2-enenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-bromophenylamino)-3-methylbut-2-enenitrile(264907-65-5)
• EPA Substance Registry System: 2-(4-bromophenylamino)-3-methylbut-2-enenitrile(264907-65-5)

Safety Data

• Hazardous Substances Data: 264907-65-5(Hazardous Substances Data)

Upstream product

• 151-50-8 potassium cyanide 
• 264907-55-3 (4-Bromo-phenyl)-[2-chloro-2-methyl-prop-(E)-ylidene]-amine 
• 106-40-1 4-bromo-aniline 
• 5804-85-3 diethylaluminium cyanide 

Downstream Products

• 2493-02-9 4-bromophenyl isocyanate 
• 503548-50-3 2-[N-(4-bromophenyl)-2-(4-bromophenylimino)-2-cyano-1,1-dimethylethylamino]-3-methylbut-2-enenitrile 
• 264907-75-7 2-[(E)-4-Bromo-phenylimino]-3-hydroperoxy-3-methyl-butyronitrile 

Relevant articles and documents

Reactions of 2-[(2-arylimino-2-cyano-1,1-dimethylethyl)arylamino]-3-methylbut-2-enenitrile with copper(II) acetate: Synthesis of 2-(2,3-dihydro-2,2-dimethyl-3-oxo-1H-indol-1-yl)-3-methylbut-2-enenitriles

Treatment of 2-[(2-arylimino-2-cyano-1,1-dimethylethyl)arylamino]-3-methylbut-2-enenitrile 15, prepared by reactions of N-aryl α-cyanoenamines 3 with Cu(OAc)2·H2O (2 equiv.) in the presence of pyridine (2 equiv.) in EtOH at reflux, and with Cu(OAc)2·H2O (1 equiv.) in HOAc at reflux gave 2-(2,3-dihydro-2,2-dimethyl-3-oxo-1H-indol-1-yl)-3-methylbut-2-enenitriles 11 in moderate to good yields.