26560-38-3

Basic information

• Product Name: L-Glutamic acid, N-4-(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methylaminobenzoyl-, calcium salt (1:1)
• Synonyms: L-Glutamic acid, N-4-(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methylaminobenzoyl-, calcium salt (1:1);Nsc173328;5-Methyltetrahydrofolate calcium;calciuM dihydride - N-[(4-{[(2-aMino-5-Methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)Methyl]aMino}phenyl)carbonyl]glutaMic acid;5-Methyltetrahydrofolate calciuM (raceMate);CalciuM N5-Methyltetrahydrofolate;Calcium 2-(4-(((2-amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido);5-Methyl-6(RS)-tetrahydrofolate calciuM salt
• CAS NO: 26560-38-3
• Molecular Formula: C20H23CaN7O6
• Molecular Weight: 497.51792
• Mol File: 26560-38-3.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: L-Glutamic acid, N-4-(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methylaminobenzoyl-, calcium salt (1:1)(CAS DataBase Reference)
• NIST Chemistry Reference: L-Glutamic acid, N-4-(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methylaminobenzoyl-, calcium salt (1:1)(26560-38-3)
• EPA Substance Registry System: L-Glutamic acid, N-4-(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methylaminobenzoyl-, calcium salt (1:1)(26560-38-3)

Safety Data

• Hazardous Substances Data: 26560-38-3(Hazardous Substances Data)

Usage

Description

L-Glutamic acid, N-4-(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methylaminobenzoyl-, calcium salt (1:1) is a complex organic compound that is the calcium salt of levomefolic acid. It is a white to slightly yellowish powder and has been proposed for the treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers.

Uses

Used in Pharmaceutical Industry:
L-Glutamic acid, N-4-(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methylaminobenzoyl-, calcium salt (1:1) is used as a therapeutic agent for the treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers. It acts on these conditions by inhibiting photosensitization reactions and strand breaks in DNA, and reducing total serum homocysteine levels in orthotopic liver transplant recipients.
Used in Research and Development:
In the field of research and development, L-Glutamic acid, N-4-(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methylaminobenzoyl-, calcium salt (1:1) can be used as a compound for studying its potential effects on various diseases and conditions, as well as for the development of new drugs and therapies.

Sources

Calcium methyltetrahydrofolate is a synthetic derivative of folic acid, the predominant, naturally occurring form of folate. It is synthesized by reduction of folic acid to tetrahydrofolic acid followed by methylation and diastereoselective crystallization (in water) of L-5-MTHF as its calcium salt.

storage

5-methyltetrahydrofolate calcium can be storaged under room temperature away from light.

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

InChI:InChI=1/C20H25N7O6.Ca.2H/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29;;;/h2-5,12-13,22H,6-9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H4,21,23,25,26,31);;;/q;+2;2*-1