265645-74-7

Basic information

• Product Name: C₂₉H₂₈O₅S₂
• Synonyms: C₂₉H₂₈O₅S₂
• CAS NO: 265645-74-7
• Molecular Weight: 520.67
• Mol File: 265645-74-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₉H₂₈O₅S₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₉H₂₈O₅S₂(265645-74-7)
• EPA Substance Registry System: C₂₉H₂₈O₅S₂(265645-74-7)

Safety Data

• Hazardous Substances Data: 265645-74-7(Hazardous Substances Data)

Upstream product

• 1077-28-7 Thioctic acid 
• 462-20-4 dihydrolipoic acid 
• 98-88-4 benzoyl chloride 

Downstream Products

• 265645-69-0 6,8-bis-benzoylsulfanyloctanoic acid 

Relevant articles and documents

Synthesis and anticancer evaluation of α-lipoic acid derivatives

α-Lipoic acid derivatives were synthesized and evaluated for their in vitro anticancer activities against NCI-460, HO-8910, KB, BEL-7402, and PC-3 cell lines. The results, for most compounds exhibited dose-dependent inhibitory property and several compounds had good inhibitions at the dose of 100 μg/mL. Compound 17m was further selected for in vivo evaluation against S180 xenograft in ICR mice, which had 24.7% tumor-weight inhibition through intragastric administration of 200 mg/kg of body weight. Moreover, the LD50 in mice for 17m through ig exceeded 1000 mg/kg of body weight.