2658-60-8Relevant articles and documents
GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE
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, (2021/01/22)
Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with a defect in glyoxylate metabolism, for example a disease or disorder associated with the enzyme glycolate oxidase (GO) or alterations in oxalate metabolism. Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.
METHOD FOR PRODUCING DIOL
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Paragraph 0049; 0050, (2019/03/08)
PROBLEM TO BE SOLVED: To provide a method for producing a diol having two methylol groups at one carbon atom on an alicyclic skeleton, which is inexpensive and generates a small amount of waste. SOLUTION: There is provided a method for producing a diol re
TRICYCLIC COMPOUND SERVING AS IMMUNOMODULATOR
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, (2019/01/04)
Provided are compounds of formula I and formula II or pharmaceutically acceptable salts of the compounds and pharmaceutical compositions thereof. The compounds of formula I and formula II or the pharmaceutically acceptable salts of the compounds provide indole 2,3-dioxygenase (IDO) inhibitory activity and are capable of treating IDO-mediated immunosuppressive diseases, such as infectious diseases or cancer.