26619-93-2

Basic information

• Product Name: (2R,5S)-6α,7α-Epoxyaspidofractinine-3β-carboxylic acid methyl ester
• Synonyms: (2R,5S)-6α,7α-Epoxyaspidofractinine-3β-carboxylic acid methyl ester;Venalstonidine
• CAS NO: 26619-93-2
• Molecular Formula: C21H24 N2 O3
• Molecular Weight: 352.4269
• Mol File: 26619-93-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 526.6°Cat760mmHg
• Flash Point: 272.3°C
• Appearance: /
• Density: 1.41g/cm³
• Vapor Pressure: 3.52E-11mmHg at 25°C
• Refractive Index: 1.688
• CAS DataBase Reference: (2R,5S)-6α,7α-Epoxyaspidofractinine-3β-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,5S)-6α,7α-Epoxyaspidofractinine-3β-carboxylic acid methyl ester(26619-93-2)
• EPA Substance Registry System: (2R,5S)-6α,7α-Epoxyaspidofractinine-3β-carboxylic acid methyl ester(26619-93-2)

Safety Data

• Hazardous Substances Data: 26619-93-2(Hazardous Substances Data)

Usage

Description

(2R,5S)-6α,7α-Epoxyaspidofractinine-3β-carboxylic acid methyl ester is a complex alkaloid compound derived from the plant Melodinus australis. Its structure has been elucidated through spectroscopic data, revealing it to be 6α,7α-epoxykopsinine. This unique molecular configuration endows it with specific properties that can be harnessed for various applications.

Uses

Used in Pharmaceutical Industry:
(2R,5S)-6α,7α-Epoxyaspidofractinine-3β-carboxylic acid methyl ester is utilized as a bioactive compound for its potential medicinal properties. Given its alkaloid nature, it may exhibit pharmacological effects that can be beneficial in the development of new drugs, particularly in the treatment of various diseases.
Used in Chemical Research:
In the field of chemical research, (2R,5S)-6α,7α-Epoxyaspidofractinine-3β-carboxylic acid methyl ester serves as a subject of study for understanding the structure-activity relationships of alkaloids. Its unique stereochemistry and epoxy groups may provide insights into the design of novel chemical entities with improved therapeutic profiles.
Used in Natural Product Chemistry:
(2R,5S)-6α,7α-Epoxyaspidofractinine-3β-carboxylic acid methyl ester is employed as a reference compound in natural product chemistry. Its isolation from Melodinus australis contributes to the understanding of the plant's chemical constituents and may lead to the discovery of new bioactive principles with potential applications in medicine and other fields.

References

Linde, Helv. Chim. Acta, 48, 1822 (1965) Linde, Pharm. Acta Helv., 45, 248 (1970)

InChI:InChI=1/C21H24N2O3/c1-25-17(24)13-10-19-6-7-21(13)20(12-4-2-3-5-14(12)22-21)8-9-23(18(19)20)11-15-16(19)26-15/h2-5,13,15-16,18,22H,6-11H2,1H3/t13-,15-,16-,18-,19+,20?,21+/m0/s1