266679-60-1

Basic information

• Product Name: 4-(2-morpholin-4-yl-ethoxy)-benzaldehyde oxime
• Synonyms: 4-(2-morpholin-4-yl-ethoxy)-benzaldehyde oxime
• CAS NO: 266679-60-1
• Molecular Weight: 250.298
• Mol File: 266679-60-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(2-morpholin-4-yl-ethoxy)-benzaldehyde oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-morpholin-4-yl-ethoxy)-benzaldehyde oxime(266679-60-1)
• EPA Substance Registry System: 4-(2-morpholin-4-yl-ethoxy)-benzaldehyde oxime(266679-60-1)

Safety Data

• Hazardous Substances Data: 266679-60-1(Hazardous Substances Data)

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 622-40-2 2-(morpholin-4-yl)ethanol 
• 82625-45-4 4-(2-morpholin-4-yl-ethoxy)-benzaldehyde 

Downstream Products

• 266679-73-6 4-(2-morpholin-4-yl-ethoxy)-benzaldehyde O-(3,3-diethyl-4-oxo-azetidin-2-yl)-oxime 

Relevant articles and documents

Synthesis, inhibitory activity towards human leukocyte elastase and molecular modelling studies of 1-carbamoyl-4-methyleneaminoxyazetidinones

Some monocyclic β-lactam derivatives of type 3 (MAOAs) in which the leaving group (LG) on the C(4) is a methyleneaminoxy moiety, were synthesised and tested in vitro and in vivo for their inhibitory activity towards human leukocyte elastase (HLE). Some compounds showed an appreciable in vitro inhibitory activity against this enzyme. Effects on the anti-HLE activity due to the nature of the substituents R and R1 present on their LG were observed and rationalised by means of molecular modelling techniques. The results of in vivo pharmacological tests indicated that MAOAs, while showing an inhibitory activity on the haemorrhage induced by HLE, did not exhibit any effects due to the R and R1 substituents. (C) 2000 Editions scientifiques et medicales Elsevier SAS.