26704-17-6

Basic information

• Product Name: 2(3H)-Furanone, dihydro-4-methyl-5-phenyl-, (4R,5R)-rel-
• CAS NO: 26704-17-6
• Molecular Formula: C11H12O2
• Molecular Weight: 176.215
• Mol File: 26704-17-6.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: 2(3H)-Furanone, dihydro-4-methyl-5-phenyl-, (4R,5R)-rel-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Furanone, dihydro-4-methyl-5-phenyl-, (4R,5R)-rel-(26704-17-6)
• EPA Substance Registry System: 2(3H)-Furanone, dihydro-4-methyl-5-phenyl-, (4R,5R)-rel-(26704-17-6)

Safety Data

• Hazardous Substances Data: 26704-17-6(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 873-66-5 1-propenylbenzene 
• 64-19-7 acetic acid 
• 53138-45-7 5-phenyl-2,5-dihydrofuran-2-one 
• 75-16-1 methylmagnesium bromide 
• 7315-67-5 3-methyl-4-oxo-4-phenylbutanoic acid 
• 75228-40-9 trans-2-methyl-3-phenyl-1,1-cyclopropanedicarboxylic acid 
• 75228-40-9 cis-2-methyl-3-phenyl-1,1-cyclopropanedicarboxylic acid 
• 144175-96-2 (E)-4-Dimethylsilanyloxy-3-methyl-4-phenyl-but-2-enoic acid methyl ester 
• 16650-28-5 2-hydroxy-4-methyl-5-phenyloxolane 
• 4393-06-0 1-Phenyl-2-propen-1-ol 
• 7287-39-0 4-(2-vinyloxy-ethoxy)-butan-1-ol 
• 36293-42-2 2-methyl-1-phenyl-4-pentenol 
• 100-52-7 benzaldehyde 

Downstream Products

• 69573-51-9 3-Methyl-4-phenylbutansaeure-methylester 

Relevant articles and documents

Chemo- and Stereoselective Crotylation of Aldehydes and Cyclic Aldimines with Allylic gem-Diboronate Ester

We report a highly chemo- and stereoselective crotylation of aldehydes and cyclic aldimines with allylic-gem-diboronate ester as a new type of organoboron reagent. The allylic-gem-diboronate ester undergoes the crotylation with aldehydes and cyclic aldimines in excellent stereoselectivity, forming anti-5,6-disubstituted oxaborinin-2-ols or (E)-δ-boryl-anti-homoallylic amines in high efficiency. The reaction shows a wide range of substrate scope and excellent functional group tolerance. The synthetic applications of the obtained products, including stereospecific C-C, C-O, and C-Cl bond formation, are also demonstrated.

Regio- and stereoselective nickel-catalyzed homoallylation of aldehydes with 1,3-dienes

Ni(acac)2 catalyzes homoallylation of aldehydes with 1,3-dienes in the presence of triethylborane. Triethylborane serves as a reducing agent delivering a formal hydride to the C2 position of 1,3-dienes, thus generating a formal homoallyl anion species and enabling the novel homoallylation of aldehydes. The reaction proceeds smoothly at room temperature in the absence of any phosphane or nitrogen ligands and is highly regioselective and stereoselective for a wide variety combination of aldehydes and 1,3-dienes: e.g., isoprene and benzaldehyde combine to give a mixture of anti- and syn-1-phenyl-3-methyl-4-penten-1-ol (2.2) in a ratio of 15:1 in 90% yield. Under the conditions, sterically congested aliphatic aldehydes and ketones show low yields. In such cases, diethylzinc serves as a substitute for triethylborane and yields the expected products in good yields with similarly high regio- and stereoselectivity. 1,3-Cyclohexadiene is one exception among 24 kinds of dienes examined and undergoes allylation (not homoallylation) selectively.

Reactivity of α-(benzoyloxy)crotylstannane with aldehydes in liquid phase and on solid support. Synthesis of substituted lactones

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