26708-48-5

Basic information

• Product Name: (E)-1-(4-ethylphenyl)-3-phenylprop-2-en-1-one
• Synonyms: (E)-1-(4-ethylphenyl)-3-phenylprop-2-en-1-one
• CAS NO: 26708-48-5
• Molecular Weight: 236.313
• Mol File: 26708-48-5.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: (E)-1-(4-ethylphenyl)-3-phenylprop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(4-ethylphenyl)-3-phenylprop-2-en-1-one(26708-48-5)
• EPA Substance Registry System: (E)-1-(4-ethylphenyl)-3-phenylprop-2-en-1-one(26708-48-5)

Safety Data

• Hazardous Substances Data: 26708-48-5(Hazardous Substances Data)

Usage

Description

(E)-1-(4-ethylphenyl)-3-phenylprop-2-en-1-one, commonly known as chalcone, is a yellow crystalline compound that belongs to the chalcone family of organic compounds. It is found in various plant species and is recognized for its potential anti-inflammatory, antioxidant, and anti-cancer properties. Chalcone is also utilized in the synthesis of bioactive compounds and has applications in the pharmaceutical, food, electronic, and textile industries.

Uses

Used in Pharmaceutical Industry:
Chalcone is used as an intermediate compound for the synthesis of various pharmaceuticals due to its potential anti-inflammatory, antioxidant, and anti-cancer properties. It plays a crucial role in the development of new drugs that can address a range of health conditions.
Used in Food Industry:
As a flavoring agent, chalcone is used in the food industry to enhance the taste and aroma of various products. Its natural origin and beneficial properties make it a preferred choice for the development of flavors that are both appealing and healthy.
Used in Electronic Industry:
Chalcone has potential applications in the development of new materials for electronic devices. Its unique properties can be harnessed to create innovative components that can improve the performance and efficiency of electronic products.
Used in Textile Industry:
In the textile industry, chalcone is used as a dye. Its vibrant color and ability to produce a range of hues make it a valuable resource for the creation of colorful and visually appealing fabrics.
Overall, (E)-1-(4-ethylphenyl)-3-phenylprop-2-en-1-one, or chalcone, is a versatile compound with a wide range of applications across different industries, from healthcare to consumer products, showcasing its significance in modern society.

Upstream product

• 478282-09-6 1-(4-ethylphenyl)-3-phenylprop-2-yn-1-ol 
• 536-74-3 phenylacetylene 
• 4748-78-1 4-ethylbenzylaldehyde 
• 40307-11-7 1-ethyl-4-ethynylbenzene 
• 100-52-7 benzaldehyde 
• 100-42-5 styrene 
• 201230-82-2 carbon monoxide 
• 25309-64-2 4-ethyl-1-iodobenzene 
• 1585-07-5 1-bromo-4-ethylbenzene 
• 937-30-4 4-ethylacetophenone 
• 100-51-6 benzyl alcohol 

Downstream Products

• 1334222-43-3 3-(4-ethylphenyl)-1-methyl-5-phenyl-4,5-dihydro-1H-pyrazole 
• 1221962-90-8 5-(4-ethylphenyl)-5-oxo-3-phenylpentanoic acid 
• 1221962-89-5 diethyl 2-(3-(4-ethylphenyl)-3-oxo-1-phenylpropyl)malonate 
• 1247902-11-9 3-cyano-2-(1H-indol-3-yl)-4-phenyl-6-(4-ethylphenyl)pyridine 
• 101854-98-2 1-(4-Ethyl-phenyl)-3-methoxyamino-3-phenyl-propan-1-one 
• 43008-74-8 1-(4-ethylphenyl)-3-phenylpropane-1-one 
• 95437-37-9 1-(4-ethyl-phenyl)-3-anilino-3-phenyl-propan-1-one 
• 102692-47-7 4'-ethyl-cis-chalcone 
• 1342310-57-9 4-(4-ethylphenyl)-6-phenyl-5,6-dihydropyrimidin-2(1H)-one 

Relevant articles and documents

Continuous-flow hydration-condensation reaction: Synthesis of αβ-unsaturated ketones from alkynes and aldehydes by using a heterogeneous solid acid catalyst

A simple, practical and efficient continuous-flow hydration-condensation protocol was developed for the synthesis of α,β-unsaturated ketones starting from alkynes and aldehydes by employing a heterogeneous catalyst in a flow microwave. The procedure presents a straightforward and convenient access to valuable differently substituted chalcones and can be applied on multigram scale.

DBU-Catalyzed Rearrangement of Secondary Propargylic Alcohols: An Efficient and Cost-Effective Route to Chalcone Derivatives

A 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU)-catalyzed rearrangement of diarylated secondary propargylic alcohols to give α,β-unsaturated carbonyl compounds has been developed. The typical 1,3-transposition of oxy functionality, characteristic of Mayer-Schuster rearrangements, is not observed in this case. A broad substrate scope, functional-group tolerance, operational simplicity, complete atom economy, and excellent yields are among the prominent features of the reaction. Additionally, the photophysical properties and crystal-structure-packing behavior of selected compounds were investigated and found to be of interest.

A new solid acid catalyst FeCl3/bentonite for aldol condensation under solvent-free condition

For the first time, a new solid acid catalyst has been used for the synthesis of aryl chalcones under solvent free conditions. A simple method (solid dispersion method) has been adopted for the synthesis of FeCl3/bentonite. The prepared catalyst has been characterized by different characterization techniques. A series of E-1-(substituted phenyl)-3-(1-pyrenyl)-2-propen-1-ones have been synthesized using FeCl3/bentonite under microwave-assisted solvent-free conditions. The yields are in the range from 80 to 88%. All the synthesized chalcones have been characterized by their physical constants, analytical, IR, 1H and 13C NMR spectral data. This catalyst can be reused for further runs (after fifth cycle) without decrease in activity. This catalyst gives excellent yields and is inexpensive and easily recyclable for this reaction.