26735-53-5Relevant articles and documents
Metathesis Reactions between Heavy d-8 Fluorides and I(III)-Pyridine Complexes
Albayer, Mohammad,Armendariz-Vidales, Georgina,Dutton, Jason L.,Hogan, Conor F.,Sharp-Bucknall, Lachlan,Withanage, Nilan
, (2020)
The reaction between trans-[AuF2(pyridine)2]+ and [PhI(pyridine)2]2+ results in the formation of PhIF2 and [Au(pyridine)4]3+. Investigation of the reaction pathway using model Pd and Pt analogues of the gold complex indicate that the most likely mechanism is attack by the Au-F onto the I(III), rather than a redox process. This demonstrates that the Au(III)-F fragment can behave in a nucleophilic manner even in a relatively electron-poor cationic complex.
Targeted fluorination with the fluoride ion by manganese-catalyzed decarboxylation
Huang, Xiongyi,Liu, Wei,Hooker, Jacob M.,Groves, John T.
supporting information, p. 5241 - 5245 (2015/04/27)
We describe the first catalytic decarboxylative fluorination reaction based on the nucleophilic fluoride ion. The reported method allows the facile replacement of various aliphatic carboxylic acid groups with fluorine. Moreover, the potential of this method for PET imaging has been demonstrated by the successful 18F labeling of a variety of carboxylic acids with radiochemical conversions up to 50-%, representing a targeted decarboxylative 18F labeling method with no-carrier-added [18F]fluoride. Mechanistic probes suggest that the reaction proceeds through the interaction of the manganese catalyst with iodine(III) carboxylates formed in situ from iodosylbenzene and the carboxylic acid substrates. Nucleophile first: An efficient manganese porphyrin catalyzed decarboxylative fluorination reaction based on a nucleophilic fluorine source is described. The potential of the described method for use in PET imaging has been demonstrated by the successful 18F labeling of various aliphatic carboxylic acids, representing the first decarboxylative 18F labeling method with no-carrier-added [18F]fluoride.
A practical synthetic method of iodoarene difluorides without fluorine gas and mercury salts
Sawaguchi, Masanori,Ayuba, Shinichi,Hara, Shoji
, p. 1802 - 1803 (2007/10/03)
Iodoarene difluorides were synthesized in three steps from the corresponding iodoarenes without the use of dangerous reagents such as fluorine gas of harmful mercury salts.
