267668-37-1

Basic information

• Product Name: Carbamic acid, (1-methyl-2-propenyl)-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, (1-methyl-2-propenyl)-, 1,1-dimethylethyl ester (9CI);N-Boc-(+/-)-3-aminobutene;(1-Methyl-allyl)-carbamic acid tert-butyl ester
• CAS NO: 267668-37-1
• Molecular Formula: C₉H₁₇NO₂
• Molecular Weight: 171.23678
• Product Categories: N-BOC
• Mol File: 267668-37-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Carbamic acid, (1-methyl-2-propenyl)-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (1-methyl-2-propenyl)-, 1,1-dimethylethyl ester (9CI)(267668-37-1)
• EPA Substance Registry System: Carbamic acid, (1-methyl-2-propenyl)-, 1,1-dimethylethyl ester (9CI)(267668-37-1)

Safety Data

• Hazardous Substances Data: 267668-37-1(Hazardous Substances Data)

Upstream product

• 267668-23-5 N-tert-butyloxycarbonyl-N-(1-methyl-2-propenyl)benzenesulfenamide 
• 1070-19-5 N-(tert-butyloxycarbonyl) azide 
• 34375-90-1 but-3-en-2-amine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1826-67-1 vinyl magnesium bromide 
• 365441-85-6 N-(tert-butoxycarbonyl)-1-tosyleth-1-ylamine 
• 598-32-3 2-hydroxy-3-butene 
• 216959-34-1 ethyl 2-{[(tert-butoxy)carbonyl]amino}-2-oxoacetate 

Relevant articles and documents

N-Methyl Allylic Amines from Allylic Alcohols by Mitsunobu Substitution Using N-Boc Ethyl Oxamate

We report the practical, scalable synthesis of a range of N-methyl allylic amines. Primary and secondary allylic alcohols underwent a regioselective Mitsunobu reaction with readily accessible N-Boc ethyl oxamate to deliver the corresponding N-Boc allylic amines, including in enantiopure form via stereospecific substitution. Subsequent N-methylation and Boc deprotection without chromatography yielded the amine products as hydrochloride salts. This method solves the problem of converting commercially available alcohols into often volatile N-methyl allylic amines, many of which have limited commercial availability.

NOVEL BICYCLIC SULFONAMIDES FOR USE AS GLUCOCORTICOID RECEPTOR MODULATORS IN THE TREATMENT OF INFLAMMATORY DISEASES

Compounds of formula (I): or a pharmaceutically acceptable salt thereof; compositions comprising them, processes for preparing them and their use in medical therapy (for example modulating the glucocorticoid receptor in a warm blooded animal).