26780-50-7

Basic information

• Product Name: POLY(D,L-LACTIDE-CO-GLYCOLIDE)
• Synonyms: DL-LACTIDE/GLYCOLIDE COPOLYMER;LACTEL BP-0100;LACTEL BP-0200;LACTEL BP-0300;RESOMER?RG 503 H;POLY(DL-LACTIDE-CO-GLYCOLIDE) (65:35);POLY(DL-LACTIDE-CO-GLYCOLIDE) 65:35*M.W. 40,000-75,;POLY(DL-LACTIDE-CO-GLYCOLIDE) (75:25)
• CAS NO: 26780-50-7
• Molecular Formula: C10H12O8
• Molecular Weight: 260.19748
• Product Categories: Biodegradable Polymers;Lactide and Glycolide Polymers;Polymer Science;Other adjuvants;Vaccine Adjuvants;Vaccine Production;Biodegradable Polymers;Cell Culture;Core Bioreagents;Lactide and Glycolide Polymers;Lipids and Related Products;Materials Science;Polymer Science;Polymers;Research Essentials;Polyamino Acids;Random Copolymers;Amino Acids;Biochemicals and Reagents
• Mol File: 26780-50-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 285.5°C at 760 mmHg
• Flash Point: 113℃
• Appearance: White to tan/Crystalline Powder or Granules
• Vapor Pressure: 0.0028mmHg at 25°C
• Storage Temp.: −20°C
• Solubility: ethyl acetate, chloroform, acetone and THF: soluble
• CAS DataBase Reference: POLY(D,L-LACTIDE-CO-GLYCOLIDE)(CAS DataBase Reference)
• NIST Chemistry Reference: POLY(D,L-LACTIDE-CO-GLYCOLIDE)(26780-50-7)
• EPA Substance Registry System: POLY(D,L-LACTIDE-CO-GLYCOLIDE)(26780-50-7)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 26780-50-7(Hazardous Substances Data)

Usage

Description

POLY(D,L-LACTIDE-CO-GLYCOLIDE), also known as Resomer R203s, is a copolymer of 1,4-Dioxane-2,5-dione and DL-Lactide. It is a biocompatible and biodegradable synthetic polymer that is highly irregular and amorphous in structure. The copolymer is composed of different ratios of lactide and glycolide monomers, PLA stereochemistries, and end-group functionalization, making it a versatile material for various applications.

Uses

Used in Pharmaceutical Industry:
POLY(D,L-LACTIDE-CO-GLYCOLIDE) is used as a controlled release system for drugs and therapeutic agents. Its biocompatibility and biodegradability make it an ideal material for delivering macromolecular therapeutics, ensuring the sustained and targeted release of drugs in the body.
Used in Drug Delivery Systems:
POLY(D,L-LACTIDE-CO-GLYCOLIDE) is used as a carrier for drug delivery systems. Its unique properties allow for the encapsulation and controlled release of various drugs, improving their bioavailability and therapeutic outcomes. This copolymer has been employed in the development of nanoparticles, microspheres, and other drug delivery devices to enhance the efficacy and safety of drug administration.
Used in Medical Devices:
Under the brand name Vicryl, POLY(D,L-LACTIDE-CO-GLYCOLIDE) is used in the manufacturing of absorbable sutures and other medical devices. Its bioresorbable nature allows the sutures to gradually break down and be absorbed by the body, eliminating the need for removal and reducing the risk of infection.
Used in Tissue Engineering:
POLY(D,L-LACTIDE-CO-GLYCOLIDE) is used as a scaffold material in tissue engineering applications. Its biodegradability and biocompatibility make it suitable for supporting cell growth and tissue regeneration, promoting the healing process in various medical procedures.
Used in Research and Development:
Due to its unique chemical properties, such as an intrinsic viscosity of 0.15-0.25, POLY(D,L-LACTIDE-CO-GLYCOLIDE) is used in research and development for the creation of new materials and formulations. Its versatility and tunable properties make it an attractive candidate for various scientific investigations and applications.

InChI:InChI=1/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2