26829-64-1

Basic information

• Product Name: 2-Propenoyl azide, 3-phenyl-
• CAS NO: 26829-64-1
• Molecular Formula: C9H7N3O
• Molecular Weight: 173.174
• Mol File: 26829-64-1.mol
• Article Data: 37

Chemical Properties

• CAS DataBase Reference: 2-Propenoyl azide, 3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoyl azide, 3-phenyl-(26829-64-1)
• EPA Substance Registry System: 2-Propenoyl azide, 3-phenyl-(26829-64-1)

Safety Data

• Hazardous Substances Data: 26829-64-1(Hazardous Substances Data)

Upstream product

• 621-82-9 Cinnamic acid 
• 71721-74-9 trans-Zimtsaeure-p-nitrophenylester 
• 100-52-7 benzaldehyde 
• 328012-09-5 (E)-1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-phenylprop-2-en-1-one 
• 14371-10-9 (E)-3-phenylpropenal 
• 140-10-3 (E)-3-phenylacrylic acid 
• 541-41-3 chloroformic acid ethyl ester 
• 73789-33-0 3,4-dinitrophenyl cinnamate 
• 73789-34-1 p-chlorophenyl cinnamate 
• 62222-44-0 m-nitrophenyl cinnamate 
• 3538-69-0 (E)-3-phenylacryloylhydrazide 
• 108761-28-0 (carbonic acid ethyl ester)-cinnamic acid-anhydride 
• 26112-94-7 1-(3-phenylpropenoyl)-1H-benzotriazole 
• 140-10-3 cis-cinnamic acid 

Downstream Products

• 4737-20-6 cinnamoyl isocyanate 
• 74088-05-4 N,N'-distyryl-urea 
• 92581-12-9 4-trans-styryl-hepta-1,6-dien-4-ol 
• 33066-20-5 (E)-1-isocyanato-2-phenylethene 
• 1885-38-7 cinnamic nitrile 
• 88425-24-5 N-benzyloxycarbonylamino-2-phenyl-(E)-ethylene 
• 69908-98-1 morpholine-4-carboxylic acid styrylamide 
• 102-93-2 3-phenylpropionamide 
• 92-07-9 3,5-diphenylpyridine 
• 95957-92-9 2-benzyl-3,5-diphenylpyridine 
• 60-35-5 acetamide 

Relevant articles and documents

Iodine(V) reagents in organic synthesis. Dess-Martin periodinane mediated efficient one-pot oxidation of aldehydes to acyl azides

A mild, efficient and general method for the one-step preparation of acyl azides from aldehydes using Dess-Martin periodinane and sodium azide is described.

Synthesis of Acyl Phosphoramidates Employing a Modified Staudinger Reaction

A one-step synthesis of acyl phosphoramidates from a variety of functionalized acyl azides has been developed employing trimethylsilyl chloride as an activating agent in a modified Staudinger reaction. The methodology was further adapted to include the in situ generation of the acyl azides from a diverse selection of carboxylic acids and hydrazide starting synthons. The reaction scope was extended to include the synthesis of imidodiphosphates and the natural product Microcin C.

Suppressive activities of KC1–3 on HMGB1-mediated septic responses

In the present study, several decursin analogues (KC1–3) were synthesized and evaluated in terms of their anti-septic activities on high mobility group box 1 (HMGB1)-mediated septic responses and survival rate in a mouse model of sepsis. KC1 and KC3, but not KC2, significantly reduced HMGB1 release in lipopolysaccharide (LPS)-activated human umbilical vein endothelial cells (HUVECs) and attenuated the cecal ligation and puncture (CLP)-induced release of HMGB1. Additionally, in vitro analyses revealed that KC1 and KC3 both alleviated HMGB1-mediated vascular disruptions and inhibited hyperpermeability in mice, and in vivo analyses revealed that KC1 and KC3 reduced sepsis-related mortality and tissue injury. Taken together, the present results suggest that KC1 and KC3 both reduced HMGB1 release and septic mortality and, thus, may be useful for the treatment of sepsis.

Chiral phosphoric acid catalyzed enantioselective annulation of acyclic enecarbamates to: In situ -generated ortho -quinone methides

The first organocatalytic asymmetric reaction of acyclic enecarbamates with o-quinone methides is disclosed. BINOL-based phosphoric acid catalysts were found to be suitable for the annulation reaction. With 10 mol% of the TRIP catalyst, high yields as well as excellent diastereo- and enantioselectivities are achieved for a variety of 2,3,4-trisubstituted chroman products.