2683-49-0Relevant articles and documents
A Novel Reagent for Labelling Macromolecules with Intensely Luminescent Lanthanide Complexes
Lamture, Jagannath B.,Wensel, Theodore G.
, p. 4141 - 4144 (1993)
A novel bifunctional chelator, 4-iodoacetamidodipicolinic acid, has been synthesized in three steps starting with chelidamic acid, and used to prepare protein conjugates that form stable and intensely luminescent complexes with Tb(III) and Eu(III).The excited state lifetime of Tb(III) complexes with this reagent was 1.25 ms, permitting its use for ultrasensitive time-resolved luminescence assays.
Selective cytotoxicity and luminescence imaging of cancer cells with a dipicolinato-based EuIII complex
Monteiro,Machado,De Hollanda,Lancellotti,Sigoli,De Bettencourt-Dias
, p. 11818 - 11821 (2017)
Four new species [Ln(dipicNH2)3]3- (Ln = LaIII, EuIII, GdIII, TbIII), with the ligand dipicNH22- (dipic = dipicolinato), were synthesized. Incubation of the EuIII complex with glioma NG97 and pancreatic cancer PANC1 cells showed that it penetrates the cell membrane and can be used to image the cells, while also being moderately cytotoxic.
Cation Complexing Properties of Synthetic Macrocyclic Polyether-Diester Ligands Containing the Pyridine Subcyclic Unit
Bradshaw, J. S.,Maas, G. E.,Lamb, J. D.,Izatt, R. M.,Christensen J. J.
, p. 467 - 474 (2007/10/02)
Ten new macrocyclic polyether-diester compounds containing a pyridine subcyclic unit substituted in the 4 position with chloro or methoxy groups have been prepared.These compounds along with their unsubstituted pyridine analogues form strong complexes wit