26844-80-4

Basic information

• Product Name: 5-METHYL-[2,3']-BIPYRIDINE
• Synonyms: 5-METHYL-[2,3']-BIPYRIDINE;5-Methyl-[2,3']bipyridinyl
• CAS NO: 26844-80-4
• Molecular Formula: C11H10N2
• Molecular Weight: 170.2105
• Mol File: 26844-80-4.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-METHYL-[2,3']-BIPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHYL-[2,3']-BIPYRIDINE(26844-80-4)
• EPA Substance Registry System: 5-METHYL-[2,3']-BIPYRIDINE(26844-80-4)

Safety Data

• Hazardous Substances Data: 26844-80-4(Hazardous Substances Data)

Usage

General Description

5-Methyl-2,3'-bipyridine is a chemical compound with the molecular formula C12H10N2. It is a derivative of bipyridine, a type of aromatic organic compound. 5-Methyl-2,3'-bipyridine is commonly used as a ligand in coordination chemistry and can form coordination complexes with various metal ions. It is also used as a precursor in the synthesis of other chemical compounds. The presence of the methyl group on the 5-position of the bipyridine molecule can affect its reactivity and properties, making it useful for specific applications in the field of chemistry.

Upstream product

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Relevant articles and documents

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Synthesis and spectroscopic comparison of the eight methyl-2,3′-bipyridyls and identification of a hoplonemertine alkaloid as 3-methyl-2,3′-bipyridyl

The pyridyl ring is frequently found in natural products and drugs. While bipyridyls have served as useful scaffolds for development of industrial and pesticidal chemicals, their biological properties are still not well understood. Only 2,3--bipyridyl, of the six isomeric bipyridyls, has been reported as a natural product in tobacco plants and in a hoplonemertine marine worm, Amphiporus angulatus (Aa), which uses its pyridyl alkaloid-rich venom to paralyze its crustacean prey and chemically defend itself against predators. Here we report for the first time the synthesis and spectroscopic properties of all eight possible methyl 2,3′-bipyridyl isomers and use this data to identify a trace alkaloidal constituent of Aa as 3-methyl-2,3′-bipyridyl. This is only the second reported instance of a methyl-bipyridyl being found as a natural product, the first being the tobacco alkaloid 5-methyl-2,3′-bipyridyl.

SYNTHETIC COMPOUNDS AND DERIVATIVES AS MODULATORS OF SMOKING OR NICOTINE INGESTION AND LUNG CANCER

Disclosed are nicotine-related compounds that selectively inhibit cytochrome P-450 2A6 (CYP2A6), selectively inhibit cytochrome P-450 2A13 (CYP2A13), and/or selectively modulate a nicotinic acetylcholine receptor (nAChR). Also disclosed are pharmaceutical compositions comprising a compound of the invention, as well as methods of using the pharmaceutical compositions for treating or preventing a disease or disorder associated with nicotine-ingestion, or a disease or disorder amenable to treatment by selective modulation of nAChRs.