26853-31-6 Usage
Uses
Used in Liposome Preparation:
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine is used as a component in the preparation of liposomes for various applications, such as the encapsulation of muramyl tripeptide and the preparation of membrane scaffold protein 1 nanodisc.
Used in the Study of Liposomes:
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine is used as a model lipid to study the effects of non-ionic detergent on liposomes, which can lead to the development of tubular protrusions, indentations, and eventually, the bursting of liposomes at higher detergent concentrations.
Used as a Biological Marker:
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine acts as a regulator of various enzyme activities and can be used as a biological marker to indicate pathological states.
Used in the Synthesis of Reconstituted High-Density Lipoproteins:
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine may be used in the synthesis of discoidal reconstituted high-density lipoproteins.
Used in the Study of AMPA Receptor Subunit GluR1 Expression:
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPhtCho) has been shown to decrease the expression of α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor subunit GluR1 on the plasma membrane of the CA1 region of rat hippocampal slices.
Used in Biophysical Experiments and Cell Membrane Mimicry:
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine is an important phospholipid for biophysical experiments and has been used to study various subjects such as lipid rafts. It is also used in systems mimicking the cell membrane, such as Nanodiscs.
Used in Pharmaceutical Applications:
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine is used in the pharmaceutical industry for the development of drug delivery systems, aiming to improve the delivery, bioavailability, and therapeutic outcomes of various drugs.
Used in the Cosmetics Industry:
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine is used in the cosmetics industry for its emulsifying and stabilizing properties, contributing to the formulation of creams, lotions, and other skincare products.
Used in the Food Industry:
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine is used in the food industry as an additive to improve the texture, stability, and shelf life of various products.
Biochem/physiol Actions
1-palmitoyl-2-oleoyl-glycero-3-phosphocholine (POPC)or 16:0-18:1 PC plays an important role as a lung surfactant and reduces surface tension. POPC mimics natural cell membrane and may be useful for unsaturated lipids oxidation studies. Its interaction with ozone leads to oxidative decomposition at the oleoyl strand C-C moiety.
Check Digit Verification of cas no
The CAS Registry Mumber 26853-31-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,8,5 and 3 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 26853-31:
(7*2)+(6*6)+(5*8)+(4*5)+(3*3)+(2*3)+(1*1)=126
126 % 10 = 6
So 26853-31-6 is a valid CAS Registry Number.
InChI:InChI=1/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20+/t40-/m1/s1
26853-31-6Relevant articles and documents
Treatment of age-related memory impairment
-
Page/Page column 7-8, (2008/06/13)
Symptoms, including biochemical correlates, of age-related memory loss (ARML) in a mammal are beneficially affected by administering to the mammal small doses of bodies, such as liposomes, of a size resembling that of mammalian cells, the bodies having phosphate glycerol head groups presented exteriorly on their surfaces. Preferred are liposomes comprised of 50-100% phosphatidylglycerol, with the phosphoglycerol headgroups thereof exteriorly presented.
Synthesis of a small library of mixed-acid phospholipids from D-mannitol as a homochiral starting material
Xia, Jie,Hui, Yong-Zheng
, p. 1659 - 1663 (2007/10/03)
Synthesis of a series of mixed-acid phospholipids containing a polyunsaturated fatty acid using a newly protecting strategy are described. Thus, benzyl and methyl α-(2,4-dinitrophenyl)acetic acid which were respectively removed by BCl3 and 354 nm light are used as protecting groups.
Liposome-Mediated Enzymatic Synthesis of Phosphatidylcholine as an Approach to Self-Replicating Liposomes
Schmidli, Peter Kurt,Schurtenberger, Peter,Luisi, Pier Luigi
, p. 8127 - 8130 (2007/10/02)
The four enzymes of the salvage pathway for phosphatidylcholine synthesis sn-glycerol-3-phosphate acyltransferase, 1-acyl-sn-glycerol-3-phosphate acyltransferase, phosphatidate phosphatase, and cytidinediphosphocholine phosphocholinetransferase were simul
