268568-12-3

Basic information

• Product Name: 2-(3-ethoxycarbonyl-propionylamino)-5-iodo-benzoic acid ethyl ester
• CAS NO: 268568-12-3
• Molecular Weight: 419.216
• Mol File: 268568-12-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3-ethoxycarbonyl-propionylamino)-5-iodo-benzoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-ethoxycarbonyl-propionylamino)-5-iodo-benzoic acid ethyl ester(268568-12-3)
• EPA Substance Registry System: 2-(3-ethoxycarbonyl-propionylamino)-5-iodo-benzoic acid ethyl ester(268568-12-3)

Safety Data

• Hazardous Substances Data: 268568-12-3(Hazardous Substances Data)

Upstream product

• 14794-31-1 ethyl 3-(chloroformyl)propionate 
• 268568-11-2 ethyl 2-amino-5-iodobenzoate 
• 5326-47-6 2-amino-5-iodobenzoic acid 

Downstream Products

• 252894-30-7 3-(6-oxo-9-trifluromethyl-5,6,7,12-tetrahydro-indolo[3,2-d]benzazepin-2-yl)-propionitrile 

Relevant articles and documents

2-Substituted paullones: CDK1/cyclin B-inhibiting property and in vitro antiproliferative activity

9-Trifluoromethyl-paullones with a carbon chain in the 2-position were synthesized by palladium-catalyzed coupling reactions of a 2-iodoprecursor with terminal alkenes or alkynes, respectively. The introduction of a 2-cyanoethyl substituent led to a significant enhancement of CDK1/cyclin B inhibiting property and in vitro antiproliferative activity. (C) 2000 Elsevier Science Ltd. All rights reserved.