26863-63-8

Basic information

• Product Name: N-cyclohexylnaphthalen-1-amine
• Synonyms: N-cyclohexylnaphthalen-1-amine;N-Cyclohexyl-1-naphthalenamine
• CAS NO: 26863-63-8
• Molecular Formula: C₁₆H₁₉N
• Molecular Weight: 225.32876
• Mol File: 26863-63-8.mol
• Article Data: 15

Chemical Properties

• Melting Point: 76-78 °C
• Boiling Point: 195-200 °C(Press: 2 Torr)
• Appearance: /
• Density: 1.096±0.06 g/cm3(Predicted)
• PKA: 5.46±0.20(Predicted)
• CAS DataBase Reference: N-cyclohexylnaphthalen-1-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-cyclohexylnaphthalen-1-amine(26863-63-8)
• EPA Substance Registry System: N-cyclohexylnaphthalen-1-amine(26863-63-8)

Safety Data

• Hazardous Substances Data: 26863-63-8(Hazardous Substances Data)

Upstream product

• 108-85-0 1-bromocyclohexane 
• 134-32-7 1-amino-naphthalene 
• 90-11-9 1-Bromonaphthalene 
• 108-91-8 cyclohexylamine 
• 108-94-1 cyclohexanone 
• 13922-41-3 1-Naphthylboronic acid 
• 6921-40-0 1-azidonaphthalene 
• 145412-54-0 dicyclohexyl(((trifluoromethyl)sulfonyl)oxy)borane 
• 108-93-0 cyclohexanol 
• 108-95-2 phenol 
• 86-57-7 1-Nitronaphthalene 
• 86-53-3 1-Cyanonaphthalene 

Relevant articles and documents

Nickel-Catalyzed Amination of Aryl Nitriles for Accessing Diarylamines through C?CN Bond Activation

A nickel-catalyzed amination to access diarylamines has been developed through C?CN bond activation of aryl nitriles with anilines. In this developed catalytic protocol, various aromatic and heteroaromatic nitriles could be utilized as the electrophiles to couple with substituted anilines. A diversity of diarylamines were obtained in 15–95% yields. (Figure presented.).

Well-Designed N-Heterocyclic Carbene Ligands for Palladium-Catalyzed Denitrative C-N Coupling of Nitroarenes with Amines

The C-N bond formation is one of the fundamental reactions in organic chemistry, because of the widespread presence of amine moieties in pharmaceuticals and biologically active compounds. Palladium-catalyzed C-N coupling of haloarenes represents one of the most efficient approaches to aromatic amines. Nitroarenes are ideal alternative electrophilic coupling partners, since they are inexpensive and readily available. The denitration and cross-coupling using nitroarenes as the electrophilic partners is challenging, because of the low reactivity of the Ar-NO2 bond toward oxidative addition. We report here the C-N coupling of nitroarenes and amines using palladium/5-(2,4,6-triisopropylphenyl)imidazolylidene[1,5-a]pyridines as the catalyst. The ligands are readily available from commercial chemicals. The reaction shows broad substrate scope and functional group tolerance. The method is applicable to both aromatic and aliphatic amines, and many secondary and tertiary aromatic amines bearing various functional groups were obtained in high yields.

Room-temperature Cu-catalyzed: N -arylation of aliphatic amines in neat water

A room-temperature and PTC-free copper-catalyzed N-arylation of aliphatic amines in neat water has been developed. Using a combination of CuI and 6,7-dihydroquinolin-8(5H)-one oxime as the catalyst and KOH as the base, a wide range of aliphatic amines are arylated with various aryl and heteroaryl halides to give the corresponding products in up to 95% yield.