26889-93-0

Basic information

• Product Name: L-Amoxicillin
• Synonyms: (2S,5R,6R)-6-((S)-2-Amino-2-(4-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo;(2S,5R,6R)-6-[[(2S)-2-amino-2-(4-hydroxyphenyl)-acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo-[3.2.0]heptane-2-carboxylic acid;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2S)-amino(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[amino(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-, [2S-[2α,5α,6β(R*)]]-;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[2-amino-2-(p-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-, stereoisomer (8CI);L-Amoxicillin;Amoxicillin Related Compound B (15 mg) (L-amoxicillin);AMoxicillin EP IMpurity B
• CAS NO: 26889-93-0
• Molecular Formula: C₁₆H₁₉N₃O₅S
• Molecular Weight: 365.41
• Product Categories: Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
• Mol File: 26889-93-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 743.2±60.0 °C(Predicted)
• Appearance: /
• Density: 1.54±0.1 g/cm3(Predicted)
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Water (Slightly, Heated, Sonicated)
• PKA: 2.44±0.50(Predicted)
• CAS DataBase Reference: L-Amoxicillin(CAS DataBase Reference)
• NIST Chemistry Reference: L-Amoxicillin(26889-93-0)
• EPA Substance Registry System: L-Amoxicillin(26889-93-0)

Safety Data

• Hazardous Substances Data: 26889-93-0(Hazardous Substances Data)

Usage

Description

L-Amoxicillin, also known as Amoxicillin EP Impurity B, is an isomer of Amoxicillin (A634235), which is a semi-synthetic antibiotic belonging to the penicillin group. It possesses potent antibacterial properties and is widely used in the medical field for treating various bacterial infections.

Uses

Used in Pharmaceutical Industry:
L-Amoxicillin is used as an antibiotic for treating a wide range of bacterial infections. Its application is primarily due to its effectiveness in targeting and eliminating harmful bacteria, thereby aiding in the recovery process for patients.
Used in Medical Treatments:
L-Amoxicillin is utilized as a therapeutic agent in medical treatments to combat bacterial infections. Its use is justified by its ability to inhibit bacterial cell wall synthesis, leading to the destruction of the bacterial cell and ultimately, the resolution of the infection.

Downstream Products

• 94659-47-9 amoxicillin (2R)-piperazine-2',5'-dione 
• 94659-47-9 amoxicillin (2S)-piperazine-2',5'-dione 
• 129880-94-0 6-[2-(4-Hydroxy-phenyl)-2-(5-methyl-6-thioxo-[1,3,5]thiadiazinan-3-yl)-acetylamino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 
• 129867-32-9 6-[2-(5-Ethyl-6-thioxo-[1,3,5]thiadiazinan-3-yl)-2-(4-hydroxy-phenyl)-acetylamino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 
• 129867-33-0 6-[2-(4-Hydroxy-phenyl)-2-(5-propyl-6-thioxo-[1,3,5]thiadiazinan-3-yl)-acetylamino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 
• 129867-36-3 6-[2-(4-Hydroxy-phenyl)-2-(5-isopropyl-6-thioxo-[1,3,5]thiadiazinan-3-yl)-acetylamino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 
• 129880-95-1 6-[2-(4-Hydroxy-phenyl)-2-(5-isobutyl-6-thioxo-[1,3,5]thiadiazinan-3-yl)-acetylamino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 
• 129867-34-1 6-[2-(5-Butyl-6-thioxo-[1,3,5]thiadiazinan-3-yl)-2-(4-hydroxy-phenyl)-acetylamino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 
• 129867-37-4 6-{2-(4-Hydroxy-phenyl)-2-[5-(3-methyl-butyl)-6-thioxo-[1,3,5]thiadiazinan-3-yl]-acetylamino}-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 
• 129867-35-2 6-[2-(4-Hydroxy-phenyl)-2-(5-pentyl-6-thioxo-[1,3,5]thiadiazinan-3-yl)-acetylamino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 
• 129867-38-5 6-[2-(5-Benzyl-6-thioxo-[1,3,5]thiadiazinan-3-yl)-2-(4-hydroxy-phenyl)-acetylamino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 
• 129867-40-9 6-[2-(5-Furan-2-ylmethyl-6-thioxo-[1,3,5]thiadiazinan-3-yl)-2-(4-hydroxy-phenyl)-acetylamino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 
• 129867-39-6 6-[2-(4-Hydroxy-phenyl)-2-(5-phenethyl-6-thioxo-[1,3,5]thiadiazinan-3-yl)-acetylamino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 

Relevant articles and documents

α-Keto aldehydes as enhancing agents of gastro-intestinal drug absorption

A method and drug form enhancing the absorption of a rectally or orally administered drug from the rectal compartment into the blood stream of a warm blooded animal. The method includes the steps of preparing a drug form capable of being rectally and orally administered. The drug form comprises a therapeutically effective unit dosage amount of a selected drug of the type which is capable of being absorbed into the blood stream from the gastrointestinal area and an α-keto aldehyde or salts thereof being present in the drug form in a sufficient amount to be effective in enhancing the drug absorption rate, when administering the drug form to warm blooded animals.