26891-76-9

Basic information

• Product Name: 7-Chloro-6-hydroxy-4-methoxy-6'-methylspiro[benzofuran-2(3H),1'-cyclohexane]-2',3,4'-trione
• Synonyms: 7-Chloro-6-hydroxy-4-methoxy-6'-methylspiro[benzofuran-2(3H),1'-cyclohexane]-2',3,4'-trione
• CAS NO: 26891-76-9
• Molecular Formula: C15H13ClO6
• Molecular Weight: 324.71
• Mol File: 26891-76-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 596.5±50.0 °C(Predicted)
• Appearance: /
• Density: 1.53±0.1 g/cm3(Predicted)
• PKA: 5.14±0.40(Predicted)
• CAS DataBase Reference: 7-Chloro-6-hydroxy-4-methoxy-6'-methylspiro[benzofuran-2(3H),1'-cyclohexane]-2',3,4'-trione(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Chloro-6-hydroxy-4-methoxy-6'-methylspiro[benzofuran-2(3H),1'-cyclohexane]-2',3,4'-trione(26891-76-9)
• EPA Substance Registry System: 7-Chloro-6-hydroxy-4-methoxy-6'-methylspiro[benzofuran-2(3H),1'-cyclohexane]-2',3,4'-trione(26891-76-9)

Safety Data

• Hazardous Substances Data: 26891-76-9(Hazardous Substances Data)

Upstream product

• 469-54-5 (2S,2'R)-7-chloro-4,6-dimethoxy-2'-methyl-3H-spiro[benzofuran-2,1'-cyclohexane]-3,4',6'-trione 
• 126-07-8 griseofulvin 

Downstream Products

• 20168-89-2 (2S,5’R)-7-chloro-6-hydroxy-3’,4-dimethoxy-5’-methylspiro[benzofuran-2,4’-cyclohex-2-ene]-1,3-dione 

Relevant articles and documents

Synthesis and single crystal X-ray analysis of two griseofulvin metabolites

The two phenols, 6-O-desmethyl griseofulvin and 4-O-desmethyl griseofulvin are metabolites of the antifungal drug griseofulvin. Herein, we present an improved synthesis of the 6-phenol derivative, and an unequivocal proof of both structures by single-crystal X-ray analysis.