26918-40-1 Usage
Description
(2alpha,6alpha,11R)-3-benzyl-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol hydrobromide is a complex chemical compound that serves as a hydrobromide salt of a synthetic opioid analgesic. It is characterized by its potent and selective agonist activity for the mu-opioid receptor, which contributes to its high efficacy in managing moderate to severe pain.
Uses
Used in Pharmaceutical Industry:
(2alpha,6alpha,11R)-3-benzyl-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol hydrobromide is used as an analgesic agent for its potent pain-relieving properties. It is particularly effective in treating moderate to severe pain due to its high affinity for the mu-opioid receptor.
Used in Research and Development:
(2alpha,6alpha,11R)-3-benzyl-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol hydrobromide is also utilized as a valuable tool in scientific research and the development of pain-relieving medications. Its unique pharmacological profile and complex molecular structure make it instrumental in advancing our understanding of opioid mechanisms and in the creation of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 26918-40-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,9,1 and 8 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 26918-40:
(7*2)+(6*6)+(5*9)+(4*1)+(3*8)+(2*4)+(1*0)=131
131 % 10 = 1
So 26918-40-1 is a valid CAS Registry Number.
26918-40-1Relevant articles and documents
Synthesis, in vitro, and in vivo activity of N-p-substituted-benzyl- (- )- and (+)-N-normetazocines, (-)- and (+)-N-normorphinans, N- norketobemidones, and (-)-N-nor-4,5-epoxymorphinans
May, Everette L.,Jacobson, Arthur E.,Mattson, Mariena V.,Coop, Andrew,Aceto, Mario D.,Bowman, Edward R.,Traynor, John R.,Woods, James H.,Harris, Louis S.
, p. 311 - 321 (2007/10/03)
N-benzyl- and N-p-nitrobenzyl-N-norketobemidone, and N-p-fluorobenzyl- N-normetazocine have been synthesized and found to have equivalent or higher affinity for the (σ(i)-binding site than the previously described (+)-N- benzylnormetazocine. None of the e
