26928-14-3

Basic information

• Product Name: 2-Propenoic acid, 3-(4-chlorophenyl)-2-fluoro-, ethyl ester, (2Z)-
• CAS NO: 26928-14-3
• Molecular Formula: C11H10ClFO2
• Molecular Weight: 228.651
• Mol File: 26928-14-3.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3-(4-chlorophenyl)-2-fluoro-, ethyl ester, (2Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3-(4-chlorophenyl)-2-fluoro-, ethyl ester, (2Z)-(26928-14-3)
• EPA Substance Registry System: 2-Propenoic acid, 3-(4-chlorophenyl)-2-fluoro-, ethyl ester, (2Z)-(26928-14-3)

Safety Data

• Hazardous Substances Data: 26928-14-3(Hazardous Substances Data)

Upstream product

• 401-58-1 ethyl 2-fluoro-2-iodoacetate 
• 104-88-1 4-chlorobenzaldehyde 
• 565-53-7 ethyl dibromofluoroacetate 
• 459-72-3 ethyl 2-fluoroacetate 
• 401-55-8 ethyl bromofluoroacetate 
• 210753-68-7 3-(4-Chloro-phenyl)-2-[(4-chloro-phenyl)-hydroxy-methyl]-2-fluoro-3-hydroxy-propionic acid ethyl ester 
• 7582-61-8 diethyl 2-oxo-3-fluorobutan-1,4-dioate sodium salt 
• 2356-16-3 ethyl(diethylphosphono)(fluoro)acetate 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 1479-22-7 ethyl 2-fluoro-3-oxo-3-phenylpropionate 

Downstream Products

• 1221508-35-5 (Z)-3-(4-chloro-phenyl)-2-fluoro-prop-2-en-1-ol 
• 58041-04-6 (Z)-3-(4-chlorophenyl)-2-fluoroacrylaldehyde 

Relevant articles and documents

CARBOLINE ANTIPARASITICS

The present invention provides Formula (1 ) compounds that are gamma-carbolines, Formula (1) wherein R1 a, R1 b, R1 c, R1d, R2, R3, and "— " are as defined herein; veterinary acceptable salts thereof, and stereoisomers thereof, which act as parasiticides,

P[N(i-Bu)CH2CH2]3N: Nonionic Lewis base for promoting the room-temperature synthesis of α,β-unsaturated esters, fluorides, ketones, and nitriles using Wadsworth - Emmons phosphonates

The bicyclic triaminophosphine P(RNCH2CH2) 3N (R = i-Bu, 1c) serves as an effective promoter for the room-temperature stereoselective synthesis of α,β-unsaturated esters, fluorides, and nitriles from a wide array of aromatic, aliphatic, heterocyclic, and cyclic aldehydes and ketones, using a range of Wadsworth-Emmons (WE) phosphonates. Among the analogues of 1c [R = Me (1a), i-Pr (1b), Bn (1d)], 1a and 1b performed well, although longer reaction times were involved, and 1d led to poorer yields than 1c. Functionalities such as cyano, chloro, bromo, methoxy, amino, ester, and nitro were well tolerated. We were able to isolate and characterize (by X-ray means; see above) the reactive WE intermediate species formed from 2b and 1c.

Microwave-assisted one-pot synthesis of α-fluoro-α,β- unsaturated esters under solvent-free conditions

A microwave-assisted approach for the synthesis of α-fluoro-α, β-unsaturated esters from ethyl bromofluoroacetate, aldehydes, and triphenylphosphine in the presence of Zn-Cu under solvent-free conditions was achieved. The reaction was accomplished within